Cutaneous Angiosarcoma of the Foot: A Case Report and Review of the Literature

Abstract

Primary Angiosarcoma of the skin of the foot is very rare. Angiosarcoma is typically treated with resection and wide-field postoperative radiation therapy. Chemotherapy and radiation therapy have also been used. Regardless of the treatment, the risk of local and distant relapse remains high for this disease. We present a case of an elderly patient who developed cutaneous angiosarcoma of the foot. It posed as a diagnostic dilemma at presentation. Chronic lymphedema was a possible predisposing factor. Given his age, preexisting renal dysfunction, refusal of surgery, and preference not to receive chemotherapy, the patient was ultimately treated with definitive radiotherapy. We present this case because of its rare site, unique presentation and delay in diagnosis of the condition, and attainment of an excellent response to radiation at the time of follow-up. We also review the current literature on this topic.

Individual multi-catheter mould technique in high-dose-rate brachytherapy – personalized approach in treating multifocal angiosarcoma of the face

“…Irradiation techniques used for the treatment of angiosarcoma have changed significantly, which may have an impact on the treatment results. Although published data on brachytherapy for angiosarcoma are mostly case reports, every individually approached patient and results reported are valuable because of the rarity of this disease [2,13,15,22,23].…”

“…Adjuvant irradiation plays an important role in enhancing local control and overall survival. Combination of these two modalities is the most efficient way of treatment [6,8,11,12,14,23,26,27,28,30]. Due to its advantages, HDR should be considered as one of the useful techniques in angiosarcoma management, while IMM HDR could be beneficial in the individualized approach, especially with problematic treatment area.…”

Atypical presentation of cutaneous angiosarcoma: review of the literature

“…2). Tenzarla et al 16 . described the case of a 90‐year‐old man presenting with a foot ulceration that did not respond to antibiotic and antifungal regimens, and was finally diagnosed as an angiosarcoma.…”