Cutaneous cytomegalovirus – A case of disseminated cytomegalovirus presenting with extensive ulcerative skin lesions in a renal transplant recipient

Ferguson, Jill; Mooney, Kelly L.; Saleem, Atif; Stevens, Bryan; Pinsky, Benjamin A.; Centkowski, Sierra; Zaba, Lisa C.; Ho, Dora Y.

doi:10.1111/tid.13582

Cited by 4 publications

(2 citation statements)

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“…Pneumonitis, gastrointestinal disease, hepatitis, and retinitis are the most common clinical manifestations of CMV disease described in the SOT population. Pancreatitis, nephritis, myocarditis, central nervous system (CNS) disease, and skin involvement have also been reported [15][16][17][18][19][20].…”

Section: Diagnosis Of Cytomegalovirus End-organ Disease In Solid Orga...mentioning

confidence: 99%

“…CMV can virtually affect any organ in the setting of immunosuppression. Various unusual CMV manifestations among SOT recipients have been reported, from ulcerative skin lesions [19,20,84] to urogenital/renal infections [85,86]. Most of these cases were associated with CMV viremia, but the definitive diagnosis of these rare entities relied on the demonstration of CMV in biopsied tissues.…”

Section: Other Unusual CMV End-organ Diseasesmentioning

confidence: 99%

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Human cytomegalovirus: a survey of end-organ diseases and diagnostic challenges in solid organ transplant recipients

Contreras

2022

Current Opinion in Organ Transplantation

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Purpose of reviewHuman cytomegalovirus (CMV) infection is one of the most important infectious complications in solid organ transplant (SOT) recipients, leading to significant morbidity and mortality. Therefore, early detection and prompt treatment are imperative to improve transplant outcomes. This article highlights the clinical characteristics of the most common CMV end-organ diseases in SOT recipients and their diagnostic modalities and challenges. Recent findingsCMV can cause a variety of end-organ diseases in SOT recipients. Although CMV nucleic acid amplification by polymerase chain reaction (PCR) is frequently employed to detect CMV reactivation or infection, its predictive value for various CMV end-organ diseases remains uncertain. Given the limitation of PCR or other noninvasive tests, confirmation of CMV end-organ disease may require tissue biopsy, which may not be feasible or available, or may cause untoward complications.

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Section: Diagnosis Of Cytomegalovirus End-organ Disease In Solid Orga...mentioning

confidence: 99%

Section: Other Unusual CMV End-organ Diseasesmentioning

confidence: 99%

Human cytomegalovirus: a survey of end-organ diseases and diagnostic challenges in solid organ transplant recipients

Contreras

2022

Current Opinion in Organ Transplantation

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Viral Infections

Harwood,

Sterling

2024

Rook's Textbook of Dermatology

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Viruses can cause disease in the skin or mucosa by direct infection or, via a systemic infection, produce secondary skin abnormalities. The chapter reviews the viruses associated with skin lesions, outlining the pathophysiology, the clinical features, diagnostic methods and the approaches to treatment. Primary skin infection following direct contact occurs with poxviruses, some herpesviruses and papillomaviruses leading to visible features which may be readily diagnostic. Less specific skin changes are seen with systemic infections, when infection is often via mucosae or inoculation, for example with parvovirus, measles or coronavirus and for these infections, diagnosis will usually involve body fluid analysis.

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Infliximab/prednisone

2022

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Cutaneous cytomegalovirus – A case of disseminated cytomegalovirus presenting with extensive ulcerative skin lesions in a renal transplant recipient

Cited by 4 publications

References 4 publications

Human cytomegalovirus: a survey of end-organ diseases and diagnostic challenges in solid organ transplant recipients

Human cytomegalovirus: a survey of end-organ diseases and diagnostic challenges in solid organ transplant recipients

Viral Infections

Infliximab/prednisone

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