Cutaneous finger and tongue metastases in renal cell carcinoma

Abro, Calvin; Sedhom, Ramy; Soni, Abha; Markowski, Mark C.

doi:10.1136/bcr-2019-230516

Cited by 4 publications

(4 citation statements)

References 5 publications

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“…Cutaneous metastases of RCC are commonly found on the head, chest, and abdomen [ 5 ]. Other unusual sites reported include chin [ 6 , 7 ], preauricular area [ 8 ], tongue, and fingers [ 9 , 10 ]. Cutaneous metastases from RCC tend to present as a single, rapidly growing, reddish-blue lesion.…”

Section: Discussionmentioning

confidence: 99%

“…Treatment with nivolumab/ipilimumab has shown to improve overall survival and progression-free survival compared with sunitinib [ 19 ]. Patients with metastatic RCC involving atypical sites, such as a digit and the tongue, have shown variable responses to adjuvant chemotherapy [ 9 , 10 ]. In such cases, a palliative approach has been considered [ 18 ].…”

Section: Discussionmentioning

confidence: 99%

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Facial Cutaneous Metastasis in Renal Cell Carcinoma

Lorenzo-Ríos

Cruzval-O’Reilly

Rabelo-Cartagena

2020

Cureus

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Renal cell carcinoma (RCC) is a common genitourinary malignancy of increasing incidence and significant mortality rate. Skin metastases of RCC are considered a rare phenomenon of unfavorable outcomes. We present a 75-year-old male patient who developed a rapidly evolving lesion on his left cheek four years after undergoing a right radical nephrectomy for non-metastatic RCC. Immunohistochemistry of the skin lesion was diagnostic for cutaneous metastasis of renal clear cell carcinoma, which eventually led to the detection of internal malignancy recurrence by positron emission tomography. A new facial skin lesion may unmask the underlying recurrence of RCC.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Facial Cutaneous Metastasis in Renal Cell Carcinoma

Lorenzo-Ríos

Cruzval-O’Reilly

Rabelo-Cartagena

2020

Cureus

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“…Various reports have described the spread of RCC to the head, neck, trunk, abdomen, testicles, penis, and extremities [50,[56][57][58][59][60][61][62][63][64]. The most common sites for cutaneous metastasis in RCC have been the trunk (40%), scalp (25%), and face (9%) of all metastatic lesions [65]. Other unusual reported sites include the chin, preauricular area, tongue, thigh, fingers, and axilla [50,[66][67][68].…”

Section: Distant Metastasis Of Rcc To the Skinmentioning

confidence: 99%

“…Metastases to distal extremities are rare and represent less than 0.2% of all RCC metastatic lesions. Cutaneous metastases of the fingers present as erythematous pustules on the fingertips, resembling a pyogenic granuloma [65]. There are a few reports in the literature presenting an unusual pattern of cutaneous metastatic RCC involving the testicles and the penis [56][57][58].…”

Section: Distant Metastasis Of Rcc To the Skinmentioning

confidence: 99%

The Cellular Stress and Cutaneous Manifestations in Renal Cell Carcinomas—A Narrative Review

Ene,

Nicolae,

Tampa

et al. 2024

JCM

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The carcinomas originating from the renal cortex are the most aggressive renal malignancies, with a high tendency for metastasis. Understanding the incidence of cutaneous manifestations caused by renal carcinomas is a challenge. In the first part, this article summarizes a series of factors that promote oncogenesis, invasiveness, and the ability of renal cell carcinoma (RCC) to develop secondary cutaneous manifestations. It is postulated that the cellular stress response is one of the leading causes of developing dermatological events induced by cancers located at distant sites. Furthermore, the paper provides an overview of cutaneous complications associated with renal cancer, categorized as malignant manifestations (metastases, synchronous or metachronous cutaneous malignancies associated with renal cancer), non-malignant indirect cutaneous manifestations associated with renal cancer, and treatment consequences. The data presented in this article suggest that recognizing certain cutaneous disorders could assist the physician in the early identification of renal neoplasms and could lead to a better prognosis.

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Differential Diagnosis between Oral Metastasis of Renal Cell Carcinoma and Salivary Gland Cancer

et al. 2021

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Renal cell carcinoma, which has clear cells in 70% of cases, has a high frequency of hematogenous distant metastases to lung, bone, liver, and other areas. Metastatic cancer accounts for 1 to 3% of malignant tumors in the stomatognathic region, and the metastasis of renal cell carcinoma to the oral mucosal tissue, though extremely rare, does occur. In addition, clear cells have been observed in some salivary gland cancers in the oral cavity. Therefore, the differential diagnosis of metastatic renal cell carcinoma and salivary gland cancer is important. This review discusses the differential diagnosis between metastatic renal cell carcinoma and malignant tumors of the salivary gland.

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Cutaneous finger and tongue metastases in renal cell carcinoma

Cited by 4 publications

References 5 publications

Facial Cutaneous Metastasis in Renal Cell Carcinoma

Facial Cutaneous Metastasis in Renal Cell Carcinoma

The Cellular Stress and Cutaneous Manifestations in Renal Cell Carcinomas—A Narrative Review

Differential Diagnosis between Oral Metastasis of Renal Cell Carcinoma and Salivary Gland Cancer

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