Cutaneous Gonococcal Abscess of the Abdomen in a Child

Dickson, Scott D.; Alter, Sherman J.

doi:10.1097/pec.0b013e31822c2882

Cited by 5 publications

(4 citation statements)

References 12 publications

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“…There are two possible pathogeneses of gonococcal infection of the penile raphe [2]. One is that the infection is caused by direct cutaneous inoculation, which has been supported by some reports of primary skin infection by N. gonorrhoeae [24][25][26][27]. The possible pathogenesis is that gonococci adhere to the openings, cysts, and canals of the penile raphe by a pilus adherence factor; they are then ingested by epithelial cells, within which they multiply, resulting in cytolysis.…”

Section: Discussionmentioning

confidence: 96%

Clinical Study on Gonococcal Infection of the Penile Raphe

Fan

Zhang²,

Wei

et al. 2023

Urol Int

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Introduction: Gonococcal infection of the penile raphe is rarely encountered in the clinical setting. The study aimed to understand the incidence, sites, clinical manifestations, and treatment of gonococcal infection of the penile raphe. Methods: We enrolled men with gonococcal infection of the penile raphe and men with urethral gonorrhea from January 2010 to December 2021. All patients’ demographic data and clinical characteristics were recorded. All patients were treated with ceftriaxone. Incision and drainage were performed in patients with non-ruptured abscesses. Nodules and sinus tract-like lesions that did not resolve after 1 month of treatment were excised. Results: Among 2,736 men who presented with urethral gonorrhea from January 2010 to December 2021, 5 (0.18%) had accompanying gonococcal infection of the penile raphe. An additional two men presented with gonococcal infection of the penile raphe without urethritis. Thus, 7 (0.26%; confidence interval, 0.11–0.56%) of 2,738 men had urethral gonorrhea or gonococcal infection of the penile raphe confirmed both clinically and by laboratory testing. Lesions were present in the frenulum of the prepuce and at the median aspect, proximal end, distal end, and both the proximal and distal ends of the penile raphe. The lesions manifested as abscesses, ulcers, a nodule, and a nodule with a sinus-like lesion. All lesions exhibited tenderness. All seven patients were cured after treatment. Conclusion: Gonococcal infection of the penile raphe is a rare, atypical type of involvement of the male urogenital tract by Neisseria gonorrhoeae. It may be a local complication of urethral gonorrhea or an independent primary infection. The proximal end, distal end, and median aspect of the penile raphe can be infected by N. gonorrhoeae. Cutaneous lesions present as abscesses, ulcers, nodules, and sinus-like lesions. Ceftriaxone is effective, but sinus-like lesions require surgery.

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Section: Discussionmentioning

confidence: 96%

Clinical Study on Gonococcal Infection of the Penile Raphe

Fan

Zhang²,

Wei

et al. 2023

Urol Int

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“…Pathogenesis of these infections usually involves direct inoculation of pathogens or exposure of injured skin to contaminated secretions, since gonococci cannot adhere to intact skin. Several cases of gonococcal scalp abscess in infants after intrauterine monitoring during delivery have been reported [14], as well as the case of gonococcal abscess on the abdominal wall of 22-month-old boy that originated from contact with an infected adult [15].…”

Section: Review Of Literature and Discussionmentioning

confidence: 99%

Health Care Associated Cutaneous Abscess – A Rare Form of Primary Gonococcal Infection

Vraneš¹,

Lukšić²,

Knežević³

et al. 2015

AJMCR

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A rare form of extragenital gonococcal infection was recorded after accidental exposure in laboratory during the identification of Neisseria gonorrhoeae. Three days after needlestick injury, on the left index finger of exposed technician very painful abscess developed. Beside local symptoms presented on the finger, fever or any other signs or symptoms of infection have not been observed. Oral antibiotic therapy with azithromycin was administered, and upon appearance of pus in the center of erythematous area surgical incision was performed. After incision the abscess was healed.

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“…This pathogen may also be transmitted vertically from mother to neonate during vaginal deliveries, resulting in conjunctival infection [3]. In addition to the classic presentations at mucosal sites, few cases of primary extragenital cutaneous gonorrhea have been reported [4][5][6][7][8][9]. In this case report, we describe a rare case of a 16-year-old female patient with diabetes mellitus presenting with primary extracutaneous gonorrhea infection of the finger.…”

Section: Introductionmentioning

confidence: 99%

A case of primary extragenital cutaneous gonorrhea involving the finger

Schwerdt

Butala

Hinds

et al. 2021

Reviews in Medical Microbiology

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A case of primary extragenital cutaneous gonorrhea affecting the left middle finger of a 16-year-old female patient is presented. The patient denied a history of sexual activity and the only reported symptoms were finger pain and associated lymphangitis. Wound culture was obtained from an incision, and drainage procedure was performed at an emergency room of a community hospital. Laboratory diagnosis was made at a clinical microbiology laboratory using Gram stain, agar culture, and matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). Concurrent blood cultures had no growth at 5 days. The patient was switched from Cephalexin and Trimethoprim-sulfamethoaxole to an appropriate regimen upon sensitivity testing. The patient was lost to follow-up, and it is unknown if the possibility of seeding mucosal infection, such as the pharynx, was investigated.

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Cutaneous Gonococcal Abscess of the Abdomen in a Child

Cited by 5 publications

References 12 publications

Clinical Study on Gonococcal Infection of the Penile Raphe

Clinical Study on Gonococcal Infection of the Penile Raphe

Health Care Associated Cutaneous Abscess – A Rare Form of Primary Gonococcal Infection

A case of primary extragenital cutaneous gonorrhea involving the finger

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