2014
DOI: 10.1159/000355966
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Cutaneous Human Papillomavirus Infection: Manifestations and Diagnosis

Abstract: Keratinocytes react to human papillomavirus (HPV) infection by proliferation resulting in different clinical manifestations ranging from flat warts to common warts and cauliflower-like or filiform warts. The clinical presentation may vary according to the HPV type and anatomical site. Although warts are usually a self-limiting disease, some HPV subtypes may induce malignant changes. Bowenoid papulosis is characterized by multiple flat macules or patches in the genital area that may or may not be pigmented. Rar… Show more

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Cited by 26 publications
(19 citation statements)
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“…The surfaces of the lesion mostly Fundamentals of Sexually Transmitted Infectionsare lat, dome-shaped, papillomatous and verrucous. The color of the lesions can be shiny lesh-colored, reddish-brown, violaceous or black [19,20]. It resembles clinically viral wart and histopathologically Bowen's disease.…”
Section: Bowenoid Papulosismentioning
confidence: 99%
“…The surfaces of the lesion mostly Fundamentals of Sexually Transmitted Infectionsare lat, dome-shaped, papillomatous and verrucous. The color of the lesions can be shiny lesh-colored, reddish-brown, violaceous or black [19,20]. It resembles clinically viral wart and histopathologically Bowen's disease.…”
Section: Bowenoid Papulosismentioning
confidence: 99%
“…[185] HPV induced skin cancers include cutaneous squamous cell carcinoma and superficial squamous cell carcinoma, such as Bowen's disease. [186] Approximately 30% individuals with infection develop invasive squamous cell carcinomas with 90% of these tumors correlated with HPV5 and HPV8. [36,187] Genetic susceptibility to HPV is demonstrated with epidermodysplasia verruciformis; however, HPV infection alone is not enough to develop cancerogenesis in epidermodysplasia verruciformis.…”
Section: Skin Cancermentioning
confidence: 99%
“…[185,190,191] In order to reduce the prevalence of HPV induced skin cancers, diagnosis of skin manifestations caused by HPV should be routinely checked. [186] …”
Section: Skin Cancermentioning
confidence: 99%
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“…Warts are the most common clinical manifestations of HPV infection. These lesions are arranged in the form of tumors that affect various locations, particularly the skin of the extremities, mucosa, genital skin, and oral and laryngeal mucosa [2]. Among them, cutaneous warts (CW) commonly affect the patients with immune disorders, such as systemic lupus erythematosus (SLE) -a prototype of autoimmune disease.…”
Section: Introductionmentioning
confidence: 99%