Cutaneous lesions of lymphomatoid granulomatosis Comparison with lymphomatoid papulosis

Kessler, Stephen; Lund, Herbert Z.; Leonard, Donald D.

doi:10.1097/00000372-198100320-00003

Cited by 15 publications

(7 citation statements)

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“…1,2 This histopathologic feature has also been recently reported in primary cutaneous gamma-delta T-cell lymphoma, 3 hydroa vacciniforme-like lymphoma, 4,5 and in a small percentage (about 15%) of primary cutaneous anaplastic large-cell lymphoma (PCALCL). 6 It has also been observed in rare cases of adult T-cell cutaneous leukemia/lymphoma.…”

Section: Introductionmentioning

confidence: 55%

Chronic Reparative Changes in Medium-Sized Vessels in a Case of Primary Cutaneous Anaplastic Large-Cell Lymphoma With Angioinvasive Features and Cytotoxic Phenotype

Macarenco

Oliveira

2015

The American Journal of Dermatopathology

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Angioinvasion/angiodestruction has been reported in a small subset of primary cutaneous anaplastic large-cell lymphomas (PCALCL). Recently, PCALCL with angioinvasive features and cytotoxic phenotype has been characterized as a variant associated with good clinical outcomes despite worrisome histopathologic features. We report a case of PCALCL with angioinvasive features and cytotoxic phenotype associated with reparative changes on the wall of medium-sized vessels involved by the neoplasm, including intimal fibroblastic proliferation and luminal obliteration. This vascular pattern, although previously unreported in PCALCL, is in accordance with the indolent behavior observed in this entity and provides a further link with lymphomatoid papulosis type E.

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Section: Introductionmentioning

confidence: 55%

Chronic Reparative Changes in Medium-Sized Vessels in a Case of Primary Cutaneous Anaplastic Large-Cell Lymphoma With Angioinvasive Features and Cytotoxic Phenotype

Macarenco

Oliveira

2015

The American Journal of Dermatopathology

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“…16,19,23,24 Lymph nodes and spleen are typically spared at initial diagnosis. 25 LYG occurs more commonly in men than in women and presents between the fourth and sixth decades.…”

Section: Clinical Presentationmentioning

confidence: 99%

Granulomatous Lymphoproliferative Disorders

Gangar¹,

Venkatarajan²

2015

Dermatologic Clinics

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“…The most common lesions were nodules, usually red, Superficial ulcers on extremities_3 (12) Papules _2 (8) Other (Raynaud's signs, excoriations, folliculitis)…”

Section: Skin Findingsmentioning

confidence: 99%

“…3 (12) that ranged from 0.5 to 4 cm in diameter (Fig 1). Most patients had fewer than five such lesions, distributed on the extremities and occasionally on the trunk.…”

Section: Skin Findingsmentioning

confidence: 99%

Cutaneous Signs of Lymphomatoid Granulomatosis

Carlson¹

1991

Arch Dermatol

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A retrospective review of 47 cases of lymphomatoid granulomatosis encountered between 1977 and 1990 revealed that 24 patients had skin involvement. Clinical and histologic features were noted. The dominant and most characteristic cutaneous finding was scattered nodules. Other cutaneous changes included eroded and crusted lesions, facial edema, papules, and folliculitis-like eruptions. The nodular skin lesions most often had an angiocentric and angiodestructive dense, polymorphous, lymphohistiocytic infiltrate in the dermis and fat. A minority of the cases had a lymphoma cutis type of infiltrate. Immunophenotypic analysis showed a mixed population of T cells, with helper T cells (CD4+) predominant. Our results emphasize the usefulness of the clinical and histologic examination of the skin in lymphomatoid granulomatosis. The histologic pattern of lymphomatoid granulomatosis was seen in the skin in more than half of the biopsy specimens.

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Cutaneous lesions of lymphomatoid granulomatosis Comparison with lymphomatoid papulosis

Cited by 15 publications

References 0 publications

Chronic Reparative Changes in Medium-Sized Vessels in a Case of Primary Cutaneous Anaplastic Large-Cell Lymphoma With Angioinvasive Features and Cytotoxic Phenotype

Chronic Reparative Changes in Medium-Sized Vessels in a Case of Primary Cutaneous Anaplastic Large-Cell Lymphoma With Angioinvasive Features and Cytotoxic Phenotype

Granulomatous Lymphoproliferative Disorders

Cutaneous Signs of Lymphomatoid Granulomatosis

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