Cutaneous Lesions of Lymphomatoid Granulomatosis

Abstract

Lymphomatoid granulomatosis is a rare multisystem disease involving the lungs, skin, and nervous system. The cutaneous disease may be the presenting complaint. A case with nodular and annular infiltrated lesions is reported to encourage the inclusion of lymphomatoid granulomatosis in the differential diagnosis of similar lesions. Prompt diagnosis and early long-term treatment with cyclophosphamide and prednisone can lead to prolonged remissions of this disease. If relapse occurs, prompt treatment with the same regimen may again induce a remission.

T- and B-Cutaneous Pseudolymphomas Treated by Surgical Excision and Immediate Reconstruction

“…Known etiologies include medication and vaccinations reactions, contact dermatitis, reaction to tattoo dyes and metals (gold), folliculitis, insect bites (ticks, scabies), actinic reticuloid and lymphomatoid papulosis, jewelry (gold), and trauma. [8][9][10][11][12] The inflammatory infiltrate may be bandlike, nodular, or diffuse and is composed predominantly of lymphocytes with or without the presence of other inflammatory cells. The differentiation between cutaneous pseudolymphoma and primary cutaneous lymphoma is often difficult 3 but is necessary in the choice of therapeutic options.…”