Cutaneous malignant melanoma metastatic to endometrium manifesting abnormal uterine bleeding in postmenopausal woman: a case report

Song, Hyoun Sook; Kim, Myoung-Hwan; Lee, Min Young; Jeon, Soon‐Ik; Kim, Hee Sun; Kim, Young Ah; Chun, Kyoung-Chul

doi:10.1080/01443615.2019.1588236

Cited by 2 publications

(2 citation statements)

References 6 publications

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“…1 Only a few cases of metastasis of melanoma to the bladder and endometrium have been described in the literature. 2,3 Melanomas, whether they are primary lesions or metastases, are classically hyperintense on T1-weighted images (24-47% of all cases), owing to paramagnetic elements (e.g. copper, manganese and zinc) present in melanin which shorten the T1 signal.…”

Section: Discussionmentioning

confidence: 99%

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Metastatic melanoma concurrent to the urinary bladder and endometrium: Case report

et al. 2021

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Summary We report a case of a 47‐year‐old woman with a history of acral lentiginous melanoma, left great toe subungual primary, metastatic to the lungs, brain, and spleen, presenting with lower urinary tract symptoms. She had also palpated and removed a dark mass from her vaginal canal. Magnetic resonance imaging (MRI) showed polypoidal lesions within the urinary bladder and the endometrium. The suspected differential diagnosis was endometrial and bladder melanoma metastases, based on her cancer history and MRI findings. The patient underwent cystoscopy with transurethral resection of the bladder tumor and endometrial biopsy, and pathology was consistent with metastatic melanoma. Bladder and endometrial metastatic lesions are exceedingly rare. Herein, we describe an unusual case of metastatic melanoma concurrent to the urinary bladder and endometrium.

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Section: Discussionmentioning

confidence: 99%

“…Regional lymph nodes are the most common site of initial metastasis 1 . Only a few cases of metastasis of melanoma to the bladder and endometrium have been described in the literature 2,3 …”

Section: Discussionmentioning

confidence: 99%

Metastatic melanoma concurrent to the urinary bladder and endometrium: Case report

et al. 2021

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Melanoma Metastases Arising at Unexpected Sites: Gallbladder and Uterus

et al. 2023

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Although malignant melanoma (MM) most frequently tends to metastasize to the regional lymph nodes, liver, lung and brain, several unusual sites of metastasis have been described in the literature. Among these, the metastatic involvement of gallbladder or uterus represents an exceptional event, usually associated with diffuse metastatic disease or observed as an autopsy finding. In this paper, we present two unusual cases of isolated MM metastasis to these anatomic sites, arising in a 71-year-old man and a 54-year-old woman, for whom no information on previous malignancies was known at the time of the histological examination. The clinico-pathologic features are described, emphasizing that MM metastasis must be included in the differential diagnosis when dealing with patients with a previous diagnosis of MM and onset of a novel mass/lesion even at unusual sites.

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Cutaneous malignant melanoma metastatic to endometrium manifesting abnormal uterine bleeding in postmenopausal woman: a case report

Cited by 2 publications

References 6 publications

Metastatic melanoma concurrent to the urinary bladder and endometrium: Case report

Metastatic melanoma concurrent to the urinary bladder and endometrium: Case report

Melanoma Metastases Arising at Unexpected Sites: Gallbladder and Uterus

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