2018
DOI: 10.1097/rlu.0000000000002061
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Cutaneous Manifestation of Sarcoidosis in Lower-Back Tattoo With Increased Uptake of 18F-FDG

Abstract: Sarcoidosis, a granulomatous T-cell-mediated multisystem disease with a yearly incidence of 10.9 to 35.5 cases per 100,000 in the United States, affects a variety of organ systems. Although the characteristic radiological finding of a bihilar lymphadenopathy still plays a diagnostic key role, FDG PET/CT is more sensitive in detecting and monitoring various manifestations. We present a rare case of a 37-year-old woman with bihilar, mediastinal, and abdominal lymphadenopathy in conjunction with a histologically … Show more

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Cited by 6 publications
(4 citation statements)
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“…The avidity of a FDG-PET scan relies on radio-labelled fluoro-deoxyglucose ( 18 F) uptake by cells with higher turnover and metabolic rate. 8,9 False positive results in up to 6.5 per cent can occur due to concurrent inflammation, such as post-surgical, radiation, chemotherapy or infection. 10 It is presumed that the tattoo ink inflammatory and hypersensitivity reaction is responsible for the observed PET avidity.…”
Section: Discussionmentioning
confidence: 99%
“…The avidity of a FDG-PET scan relies on radio-labelled fluoro-deoxyglucose ( 18 F) uptake by cells with higher turnover and metabolic rate. 8,9 False positive results in up to 6.5 per cent can occur due to concurrent inflammation, such as post-surgical, radiation, chemotherapy or infection. 10 It is presumed that the tattoo ink inflammatory and hypersensitivity reaction is responsible for the observed PET avidity.…”
Section: Discussionmentioning
confidence: 99%
“…These granulomas are not identical with cutaneous sarcoidosis. However, true cutaneous sarcoidosis has also been observed in tattoos but less common [49], [50].…”
Section: Tattoos As Icd’smentioning
confidence: 99%
“…Clinical adverse effects may manifest locally in the tattoo at the site of injected pigment, but it has also been suggested to reach the circulation and internal organs and exert mutagenic events. These adverse effects have a broad spectrum of clinical manifestations in the skin ranging from mild and intermittent sun sensitivity to allergy, sarcoid granulomas, neurosensitive reactions, and keratoacanthomas, which are associated with a potentially significant disease burden [3,4,[10][11][12][13]. Medically, the phenomenon has received little attention and has only recently been recognized.…”
Section: Introductionmentioning
confidence: 99%