Cutaneous melanoma incidence, mortality, and survival in Manizales, Colombia: a population-based study

Abstract

Objective We estimated the cutaneous melanoma (CM) incidence, mortality, and survival in Manizales, Colombia to establish predictors for survival. Methods This analytical cohort study used CM incident cases during 2006 to 2015 in the Manizales Cancer Registry (n = 132). Incidence and mortality rates were standardized using the direct method. Patients were followed up until 30 November 2020. Cause-specific survival was calculated using the Kaplan–Meier method for variables of interest, with the log-rank test for differences. Cox multivariate regression models were fitted. Results Incidence (per 100,000) increased from 1.6 to 3.0 in men and 2.6 to 2.8 in women during 2006–2010 to 2011–2015, respectively. Mortality was low and stable. Five-year survival was 68.7%, with significant differences according to age (hazard ratio [HR] >70 vs. ≤70 years: 3.37); histological subtype (HR for melanoma not otherwise specified and HR for nodular melanoma vs lentigo malignant melanoma and superficial spreading melanoma: 17.39 and 10.16, respectively); and clinical stage (HR stages III–IV vs. stages I–II: 5.94). Conclusion CM is characterized by increasing incidence and unfavorable prognosis, particularly in patients aged >70 years, with melanoma not otherwise specified and nodular melanoma, and advanced stages. Promoting photoprotection and early detection and management of suspicious skin lesions is crucial.

Skin health of community-living older people: a scoping review

“…Most studies ( n = 10) described self-reported skin concerns/complaints or symptoms such as pruritus [ 20 , 34 , 40 , 42 , 45 , 65 , 102 – 105 ]. Nine studies reported mortality [ 53 , 63 , 64 , 71 , 77 , 79 , 97 , 98 , 106 ] and seven studies dermatology-related medical visits [ 37 , 42 , 43 , 107 – 109 ] or hospital admissions [ 110 ]. One report described depressive disorders in individuals with and without ‘skin conditions’ [ 111 ], one a potential association between ‘skin problems’ and quality of life [ 103 ] and another the perception of whether skin conditions were bothersome [ 104 ].…”

Differences and Similarities in Epidemiology and Risk Factors for Cutaneous and Uveal Melanoma

“…However, it is important to note that this figure is not universal and may vary considerably among individual patients, influenced by diverse clinical and pathological features such as the number of involved lymph nodes, genetic alterations, and the primary tumor characteristics such as thickness and ulceration [ 91 ].…”

Determinación de la supervivencia a 5 años en pacientes con cáncer de piel melanoma diagnosticados en el Hospital SOLCA, Loja-Ecuador (2010-2020)

“…En un estudio realizado en Cuba en 2021 se obtuvo un predomino del sexo masculino del 8,1% y el 7,7% en el sexo femenino (7). Sin embargo, esto difiere con el estudio realizado por Rodríguez-Betancourt y Arias-Ortiz en donde la supervivencia a 5 años fue ligeramente mayor en el sexo femenino con el 77,3%, con respecto al sexo masculino que fue del 56,4% (8). Estos resultados muestran que la diferencia de la supervivencia con respecto al sexo es similar entre países latinoamericanos en donde la incidencia es baja.…”