Cutaneous metastases with different clinical presentations: case series and review of the literature

Abstract

Cutaneous metastasis (CM) is a rare clinical entity with an incidence of less than 10% among oncology patients. Dissemination to the skin can be via bloodstream, lymphatics, direct expansion or by seeding after surgical procedures. Skin metastases usually develop months to years after the diagnosis of the primary tumour while it may be the opposite in some rare cases. CM has various clinical presentations; diagnoses can be easily overseen as CM can mimic other dermatologic diseases. Herein, we present five different cutaneous metastasis cases, each with distinct dermatological presentation. Our main aim here is to allow dermatologists consider skin metastases in the differential diagnoses of dermatological diseases, in their clinical practice.

Cutaneous Metastases as an Initial Presentation of Neo Infiltrative Process in the Lungs: Case Report and Literature Review

“…We would like to mention the importance of mimicking skin metastasis with other skin changes and pathology, which may lead to overlooking the underlying disease. [4,5] The most common localization in clinical practice is on the chest, abdomen, head and neck. The most common manifestation is the nodular form, they are painless and firmly fixed to the skin, usually with a pinkish-red discoloration.…”

Cutaneous metastases of cervical cancer: a rare entity and possible mechanisms of dissemination

“…Among women, the most common tumours that metastasize to the skin are breast cancer, followed by colon cancer, melanoma, and ovarian carcinoma. Additionally, the most frequently affected site of metastases in men is the head and neck region, whereas in women the anterior chest wall [ 4 , 5 ].…”