Cutaneous metastasis of esophageal adenocarcinoma with an unusual presentation

Riley, S.A.; Wah, Tze Min

doi:10.1002/jcu.20295

Cited by 19 publications

(12 citation statements)

References 8 publications

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“…According to a recent report, survival differences based on histology have been observed, and the adenocarcinoma subtype had a slightly longer survival rate 16 . They suggested that the introduction of endoscopic surveillance programs for Barrett's esophagus might explain the more pronounced improvement in survival among patients with adenocarcinoma compared to patients with squamous cell carcinoma.…”

Section: Discussionmentioning

confidence: 99%

A Case of Esophageal Adenocarcinoma Metastasized to the Scalp

Park

Kim

et al. 2009

Ann Dermatol

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Cutaneous metastases from internal malignancies are, occurring in 0.5% to 9% of cases. Lung, breast, and colorectal cancers are common primary tumors that metastasize to the skin; cutaneous metastasis usually occurs on the chest wall and abdomen as asymptomatic nodular patterns. Esophageal cancer is not nearly as common as breast, lung, and colorectal cancers, and esophageal cancer rarely metastasizes to the skin. Cutaneous metastasis of esophageal cancer is rare and metastasis to the scalp is extremely rare. Only a few cases of cutaneous metastases of esophageal cancer have been reported in Korea. Most of the cases involved cutaneous metastases arising from esophageal squamous cell carcinoma; however, there have been several reports describing cutaneous metastases from esophageal adenocarcinomas. Herein, we describe a case of metastatic skin cancer that originated from esophageal adenocarcinoma. (Ann Dermatol 21(2) 164∼167, 2009)

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Section: Discussionmentioning

confidence: 99%

A Case of Esophageal Adenocarcinoma Metastasized to the Scalp

Park

Kim

et al. 2009

Ann Dermatol

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“…5 The skin lesions may be observed in different locations of the human body. 2,[6][7][8][9][10][11][12][13] We describe 2 cases of cutaneous metastases in patients diagnosed with esophageal adenocarcinoma.…”

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confidence: 99%

Cutaneous Metastases From Esophageal Adenocarcinoma

Triantafyllou

Doulami

Vrakopoulou

et al. 2015

International Surgery

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The aim of this study is to present 2 rare cases of cutaneous metastases originated from adenocarcinoma of the gastro-esophageal junction, thus, underline the need for early diagnosis and possible treatment of suspicious skin lesions among patients with esophageal malignancy. Metastatic cancer to the skin originated from internal malignancies, mostly lung cancer, breast cancer, and colorectal cancer, constitute 0.5 to 9% of all metastatic cancers. 5,8,15 Skin metastases, mainly from squamous cell carcinomas of the esophagus, are rarely reported. Cutaneous metastasis is a finding indicating progressiveness of the disease. 17 More precisely, median survival is estimated approximately 4.7 months. 2,14 This study is a retrospective review of 2 cases of patients with adenocarcinoma of the esophagus and a review of the literature. Two patients aged 60 and 32 years old, respectively, underwent esophagectomy. Both pathologic reports disclosed adenocarcinoma of the gastro-esophageal junction staged T3 N2 M0 (stage IIIB). During follow-up time, the 2 patients were diagnosed with cutaneous metastases originated from the primary esophageal tumor 11 and 4 months after surgery, respectively. The first patient is alive 37 months after diagnosis, while the second one died 16 months after surgery. Cutaneous metastasis caused by esophageal adenocarcinoma is possible. Therefore, follow-up of patients who were diagnosed with esophageal malignancy and underwent esophagectomy is mandatory in order to reveal early surgical stages.

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“…In another study published in 1995, out of 838 patients with esophageal carcinoma, only two presented with metastatic disease to the skin [3]. Esophageal carcinoma metastasizing to the skin is very uncommon with only eight published case reports found in English literature to date (Table 1) [4][5][6][7][8][9][10][11]. Our case is unique in several ways.…”

Section: Discussionmentioning

confidence: 65%