Cutaneous metastatic disease

Schwartz, Robert A.

doi:10.1016/0190-9622(95)90231-7

Cited by 407 publications

(204 citation statements)

References 265 publications

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“…It is a fibrotic process resembling the encasement in an armor of a curassiere (cavalry soldier) [7,8], leading to a progressive retraction with disappearance of the mammary gland, then the ulceration plated on the costal grill. It evolves from firm papules and nodules overlying an erythematous base to a sclerodermoid plaque [9]. Pain and pruritus may be the associated features, unlike cutaneous metastases, which usually present as asymptomatic, painless, firm or doughy skin-colored papules or nodules.…”

Section: Discussionmentioning

confidence: 99%

Untitled

2014

Glob Dermatol

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The atrophic squirrhus carcinoma is an advanced form of breast cancer, which is most often neglected by patients. These days it has become very rare. The bilaterality of this form is even more exceptional.We present a case of atrophic squirrhus breast cancer of a 58 years old woman, rural origin, which is particular for its bilaterality and rapid evolution causing the death after 22 months from the first abnormal functional sign.

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Section: Discussionmentioning

confidence: 99%

Untitled

2014

Glob Dermatol

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“…As a result of diffuse invasion of dermal lymphatic blockage, edema and eryhthema occurs (Homler et al, 1986;Schwartz, 1995;Nambi and Tharakaram, 1999;Lee et al, 2001). Dissemination is most likely to have occured via a direct spread from the affected lymph nodes to cutaneous lymphatic (Lever, 1991;Cox, 1994;Schwartz, 1995;Nambi and Tharakaram, 1999).…”

Section: Discussionmentioning

confidence: 99%

“…The clinical progression usually involves rapid enlargement of the affected area without skin ulceration (Homler et al, 1986;Lee et al, 2001;Calka, 2002;Gutierrez and Rodriguez, 2007). CE is most commonly caused by breast carcinoma, but it has also been related to other malignancies; thyroid, bladder, lung, gastric (Homler et al, 1986;Lever, 1991;Lookingbill, 1993;Wnamaker et al, 1993;Schwartz, 1995;Nambi and Tharakaram, 1999;Hamamoto et al, 2001;Calka, 2002;Gutierrez and Rodriguez, 2007). Cutaneous metastases occur in 1% to 5% of patients with visceral malignancies (Hamamoto et al, 2001;Lookingbill, 1993), Between 10% and 35% of women with operable breast cancer will experience an isolated locoregional recurrence following their primary treatment.…”

Section: Discussionmentioning

confidence: 99%

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Carcinoma Erysipeloides: A Rare Form of Cutaneous Metastases From Breast Carcinoma

POLAT¹,

POLAT²,

Işık³

et al. 2010

jecm

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We described in this case report a 62 years-old women with a history of modified radical mastectomy for an invasive ductal carcinoma of the left breast 3 years previously (StageIIIACerb-b2 (+), ER(-), PR %75 (+). Although the patient has been still receiving Aromatase inhibitor (AI) diffuse erythematous plaques with an erysipel-like appearance occured located over the left side of the anterior chest wall and extending far from the mastectomy incision through the infraclavicular area, axilla, and back including scapular region. We observed complete clinical response after this chemotherapy regimen. Today the patient has been still under following up since diagnosed with erisypeloid carcinoma without any local recurrences for 24 months.

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“…In men, the most common internal malignancies leading to cutaneous metastases are lung cancer, colon cancer, melanoma, squamous cell carcinoma of the oral cavity, and renal cell carcinoma. In women, breast cancer, colon cancer, melanoma, lung cancer, and ovarian cancer are the most common malignancies leading to cutaneous metastasis [5].…”

Section: Introductionmentioning

confidence: 99%

Innumerable Radioiodine Negative Cutaneous Metastases From Papillary Thyroid Cancer

Damle

2011

J Endocrinol Metab

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Differentiated thyroid cancer (DTC) is the most common endocrine malignancy and papillary thyroid carcinoma (PTC) accounts for a majority of these. Distant metastases, especially to the lung and bones, occur in about 10% of patients, who can still survive for many years. We report here the case of a 32 year old female who presented with multiple bilateral cervical lymphadenopathy, diagnosed as metastatic PTC on cytology. She underwent total thyroidectomy and bilateral radical neck dissection followed by radioiodine therapy. Subsequently she developed pulmonary and bone metastases, and during the course of successive radioiodine doses, presented with multiple, painless cutaneous and subcutaneous nodules which proved to be metastatic on cytopathology and immunostaining. Radioiodine uptake was not seen in these lesions, suggesting dedifferentiation of follicular cells. This case emphasizes three clinically important issues-firstly, although extremely rare, cutaneous nodules can represent metastatic PTC in patients with pre existing lung and bone lesions and portends a poorer prognosis. Secondly, these lesions may be dedifferentiated and hence not amenable to radioiodine therapy although the bone and lung lesions show radioiodine uptake. SPECT/CT helps us in determining if uptake of 131-I is in the skin lesions or underlying other sites. Redifferentiating agents may play a role in management of such disease. Lastly, immunostaining with CK19 and Thyroglobulin (Tg) can be highly useful to confirm the pathologic diagnosis.

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Cutaneous metastatic disease

Cited by 407 publications

References 265 publications

Untitled

Untitled

Carcinoma Erysipeloides: A Rare Form of Cutaneous Metastases From Breast Carcinoma

Innumerable Radioiodine Negative Cutaneous Metastases From Papillary Thyroid Cancer

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