Cutaneous Metastatic Lung Cancer: Literature Review and Report of a Tumor on the Nose from a Large Cell Undifferentiated Carcinoma

Rubinstein, Ran Y.; Baredes, Soly; Caputo, Joseph M.; Galati, Lisa; Schwartz, Robert A.

doi:10.1177/014556130007900209

Cited by 17 publications

(3 citation statements)

References 31 publications

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“…Lesions initially grow rapidly, and then more slowly, and may necrose or ulcerate (7). Metastasis to the skin is occasionally recognized as the first sign of lung cancer, before the primary tumour is diagnosed (8). In a large series of cases of skin metastases from lung malignancies, cutaneous metastasis preceded the primary lung cancer in 14% of cases (9).…”

Section: Discussionmentioning

confidence: 99%

Nasal Tip Cutaneous Metastases Secondary to Lung Carcinoma: Three Case Reports and a Review of the Literature

Chun¹,

Kim²,

Lee³

et al. 2013

Acta Derm Venerol

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Cutaneous metastatic carcinoma of the nose is a rare presentation associated with lung cancer. We report here 3 cases of cutaneous metastatic carcinoma of the nose that originated from lung cancer. Two men, age 61 and 76 years, with lung cancers were referred for evaluation of a tumour on the tip of the nose. The third patient, a 57-year-old man, had developed a rosacea-like tumour on the tip of the nose; although he had no history of internal cancer, whole-body positron-emission tomography-computed tomography revealed a primary lung cancer. Skin biopsies of all 3 cases showed metastatic squamous cell carcinoma, and all primary lung cancers were squamous cell carcinomas. Only 3 patients are described here, and further reports are needed to substantiate this interesting phenomenon. When an elderly patient presents to dermatology with a tumour on the nose with or without known internal cancer, it is necessary to approach the diagnosis with caution.

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Section: Discussionmentioning

confidence: 99%

Nasal Tip Cutaneous Metastases Secondary to Lung Carcinoma: Three Case Reports and a Review of the Literature

Chun¹,

Kim²,

Lee³

et al. 2013

Acta Derm Venerol

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“…Breast tumours metastasising to the breast or chest wall are the most common occurrence in women (39-62%), 44 while cutaneous metastases from primary lung cancers are the most frequent occurrence in men. 45 Other common sites include the head and neck (24-33.8%); back, trunk or abdomen (1-3%); groin or axilla (3-7%); and genitals (3-5%). 44 Patients with abdominal or perineal wounds may also develop sinuses or fistulae with internal body cavities, 41 which will exacerbate problems with malodour and exudate as faecal or other body substances may leak through the wound.…”

Section: Presentationmentioning

confidence: 99%

Malignant fungating wounds: epidemiology, aetiology, presentation and assessment

Alexander

2009

J Wound Care

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“…Our case illustrates a lung cancer which has metastasized both to the breast and the abdomen; however, this is quite rare; instead, most lung cancers usually involve the anterior chest, abdomen, and head and neck [ 11 , 13 – 15 ] while less common locations include the shoulder, flank, and lower and upper extremities [ 11 , 13 , 14 ]. Rare sites of metastasis include the gingiva, scrotum, perianal skin, lip, nose, burn scars, fingers, and toes [ 11 , 16 , 17 ]. Cutaneous metastases from lung cancer do not have a characteristic presentation and are often described as nodular, mobile or fixed, hard or flexible, single or multiple, and painless.…”

Section: Discussionmentioning

confidence: 99%

Lung Cancer with Skin and Breast Metastasis: A Case Report and Literature Review

Bhattarai

Schmidt

Ghosh

et al. 2015

Case Reports in Pulmonology

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Lung cancer is one of the most common cancers in America. Frequent sites of metastasis include the Hilar lymph nodes, adrenal glands, liver, brain, and bone. The following case report is of a primary lung cancer with metastases to the breast and skin. Case. A 48-year-old African American male with a past medical history of poorly differentiated left breast cancer status after modified radical mastectomy (MRM), chronic obstructive pulmonary disease, and smoking (20 pack-years) presents to the ER with progressive shortness of breath on exertion, upper back pain, and weight loss for 2 months in duration. On physical examination he is found to have a MRM scar on his left breast and a left periumbilical cutaneous mass. Chest X-ray and chest CT reveal a right upper lobe mass and biopsies from the breast, lung, and the periumbilical mass indicate a poorly differentiated carcinoma of unclear etiology; all tumor markers are negative. The patient is male and a chronic smoker; therefore the diagnosis is made as lung carcinoma with metastases to the breast and skin. Conclusion. A high index of suspicion for cutaneous metastases should be cast when investigating cutaneous pathologies in patients at risk for primary lung malignancy.

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Cutaneous Metastatic Lung Cancer: Literature Review and Report of a Tumor on the Nose from a Large Cell Undifferentiated Carcinoma

Cited by 17 publications

References 31 publications

Nasal Tip Cutaneous Metastases Secondary to Lung Carcinoma: Three Case Reports and a Review of the Literature

Nasal Tip Cutaneous Metastases Secondary to Lung Carcinoma: Three Case Reports and a Review of the Literature

Malignant fungating wounds: epidemiology, aetiology, presentation and assessment

Lung Cancer with Skin and Breast Metastasis: A Case Report and Literature Review

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