Cutaneous Methicillin-Resistant Staphylococcus aureus in a Suburban Community Hospital Pediatric Emergency Department

Kairam, N.; Silverman, Michael E.; Salo, D.; Baorto, Elizabeth; Liu, Ben; Amato, Christopher S.

doi:10.1016/j.jemermed.2009.05.015

Cited by 8 publications

(6 citation statements)

References 24 publications

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“…In agreement with earlier reports, the prevalence of MRSA in the study hospital did not vary by gender (22). However, the MRSA infection rates are significantly different between ethnic groups and the rate is clearly elevated in the Indian population.…”

Section: Discussionsupporting

confidence: 92%

Predominance and Emergence of Clones of Hospital-Acquired Methicillin-Resistant Staphylococcus aureus in Malaysia

Ghaznavi‐Rad¹,

Shamsudin²,

Sekawi³

et al. 2010

J Clin Microbiol

119

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We define the epidemiology of predominant and sporadic methicillin-resistant Staphylococcus aureus (MRSA) strains in a central teaching and referral hospital in Kuala Lumpur, Malaysia. This is done on the basis of spa sequencing, multilocus sequence typing (MLST), staphylococcal cassette chromosome mec (SCCmec) typing, and virulence gene profiling. During the period of study, the MRSA prevalence was 44.1%, and 389 MRSA strains were included. The prevalence of MRSA was found to be significantly higher in the patients of Indian ethnicity (P < 0.001). The majority (92.5%) of the isolates belonged to ST-239, spa type t037, and possessed the type III or IIIA SCCmec. The arginine catabolic mobile element (ACME) arcA gene was detected in three (1.05%) ST-239 isolates. We report the first identification of ACME arcA

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Section: Discussionsupporting

confidence: 92%

Predominance and Emergence of Clones of Hospital-Acquired Methicillin-Resistant Staphylococcus aureus in Malaysia

Ghaznavi‐Rad¹,

Shamsudin²,

Sekawi³

et al. 2010

J Clin Microbiol

119

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“…The studies, performed at medical centers in Springfield, MA [13], Denver, CO [14], and Morristown, NJ [15], were found to vary significantly with respect to both the average fraction of CA-MRSA among all S. aureus (ranging from 28% to 54% of infections), as well as with respect to the estimated plateau: the peak proportion of CA-MRSA among all S. aureus infections in the study from Denver, CO was estimated at 83%, in Morristown, NJ at 50%, and in Springfield, MA at 78%. Based on these results, the meta-analytic plateau for the fraction of CA-MRSA out of all S. aureus infections is estimated to be 65% (standard error: 11%).…”

Section: Resultsmentioning

confidence: 99%

“…The individual studies vary with respect to this limiting fraction: in Springfield, MA [13], it was estimated at 78%, in Denver, CO [14] at 83% and in Morristown, NJ [15] at 50%.…”

Section: Resultsmentioning

confidence: 99%

Epidemics of Community-Associated Methicillin-Resistant Staphylococcus aureus in the United States: A Meta-Analysis

et al. 2013

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Staphylococcus aureus is the most frequent cause of skin and soft tissue infections in humans. Methicillin-resistant strains of S. aureus (MRSA) that emerged in the 1960s presented a relatively limited public health threat until the 1990s, when novel community-associated (CA-) MRSA strains began circulating. CA-MRSA infections are now common, resulting in serious and sometimes fatal infections in otherwise healthy people. Although some have suggested that there is an epidemic of CA-MRSA in the U.S., the origins, extent, and geographic variability of CA-MRSA infections are not known. We present a meta-analysis of published studies that included trend data from a single site or region, and derive summary epidemic curves of CA-MRSA spread over time. Our analysis reveals a dramatic increase in infections over the past two decades, with CA-MRSA strains now endemic at unprecedented levels in many US regions. This increase has not been geographically homogeneous, and appears to have occurred earlier in children than adults.

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“…Although they identified some risk factors associated with MRSA, post hoc analysis demonstrated that patients who lived in a low (10%) MRSA prevalence area and who lacked three of the strongest associated risk factors would still have a 7% post-test probability of MRSA (6). No differences between MRSA and non-MRSA infections were found for gender, age, or site of infection in pediatric skin and soft tissue infections (7). A study that specifically evaluated management of superficial abscesses drained in the ED showed that there was no significant association between amount of surrounding cellulitis or abscess size with the likelihood of MRSA-positive cultures (8).…”

Section: Predictors Of Mrsa In Abscess Patientsmentioning

confidence: 99%

How Do You Treat an Abscess in the Era of Increased Community-associated Methicillin-resistant Staphylococcus Aureus (MRSA)?

Schmitz¹

2011

The Journal of Emergency Medicine

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Cutaneous Methicillin-Resistant Staphylococcus aureus in a Suburban Community Hospital Pediatric Emergency Department

Cited by 8 publications

References 24 publications

Predominance and Emergence of Clones of Hospital-Acquired Methicillin-Resistant Staphylococcus aureus in Malaysia

Predominance and Emergence of Clones of Hospital-Acquired Methicillin-Resistant Staphylococcus aureus in Malaysia

Epidemics of Community-Associated Methicillin-Resistant Staphylococcus aureus in the United States: A Meta-Analysis

How Do You Treat an Abscess in the Era of Increased Community-associated Methicillin-resistant Staphylococcus Aureus (MRSA)?

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