Cutaneous mucinosis of infancy

Long‐term follow‐up of a patient with congenital cutaneous mucinosis of infancy and description of a new case

“…CMI is extraordinarily infrequent, with only 10 cases ever reported. The very few published cases lack long‐term follow‐up, and most report that papules are persistent . In our report (case 1), with a follow‐up of 6 years, we observed an increase in the number of skin lesions in the first years of life, followed by almost complete resolution in the following years, without symptoms or signs of associated systemic disease.…”

Lichen myxedematosus: a rare group of cutaneous mucinosis

“…48 One series of three patients previously unsuccessfully treated showed a marked response when thalidomide was started. 36 Hydroxychloroquine along with PUVA and thalidomide were ineffective in another report. 49 The combination of vincristine, idarubicin, dexamethasone, and thalidomide was reported to be successful in one patient with scleromyxedema, although thalidomide had to be interrupted due to neuropathy.…”

“…There were no symptoms associated in four reported cases (Table 1). [33][34][35][36][37][38][39][40][41]…”

“…In both patients, mucin deposits within the dermal stroma were consistent with dark spaces between thin collagen fibers. In addition, spindle-shaped fibroblasts within the mucinous areaswith fusiform-to-dendritic structures -were observed to be thicker 36 Laura Atzori 2014, 37 Kołodziejczyk, Beata 2017, 38 Luo, D 2011, 39 Alvarez-Garrido 2014, 40 Gomez Sanchez, Maria Encarnacion 2016. 41 DPLM, discrete papular lichen myxedematosus; APPM, acral persistent papular mucinosis; SPM, self-healing papular mucinosis; CMI, cutaneous mucinosis of infancy; NLM, nodular lichen myxedematosus; ILC, intralesional corticosteroids; CNI, calcineurin inhibitor; DM, diabetes mellitus An Bras Dermatol.…”

Cutaneous mucinosis of infancy: a rare entity in pediatrics

“…CMI is an uncommon subtype of papular mucinosis; it can be present at birth or start in early childhood 4‐5 . Its clinical presentation is highly variable and can consist of asymptomatic papules, plaques, or nodules that generally affect the trunk and proximal limbs 4,6 . Lesions can be localized, symmetric, grouped, or linear 5 .…”