Cutaneous plasmacytosis successfully treated with narrowband ultraviolet B irradiation therapy

Yanaba, Koichi; Kajii, Takayuki; Matsuzaki, Hiroyuki; Umezawa, Yoshinori; Nakagawa, Hidemi

doi:10.1111/1346-8138.13164

Cited by 7 publications

(4 citation statements)

References 5 publications

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“…8,14 A good response was reported with 308-nm excimer lamp, with a mechanism supposedly similar to NB-UVB. 15 The present patient has not responded to topical or systemic corticosteroid therapy neither to NB-UVB and thalidomide. Despite the difficulty to achieve complete clearance with the available treatment options, the prognosis of the majority of patients with cutaneous/systemic plasmacytosis is favorable.…”

Section: Discussionmentioning

confidence: 50%

Cutaneous Plasmacytosis: Diagnostic and Therapeutic Challenge in a Patient with an Atypical Presentation

Amorim

Rosa

Buratto

et al. 2021

SPDV

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Cutaneous plasmacytosis is a rare dermatosis that is classically characterized by the presence of multiple papules and reddish- -brown nodules mainly in the trunk. It most commonly affects elderly Asians, with few reports in Caucasians and young patients. On histopathology there is a polyclonal proliferation of mature plasm cells. The objective of this report is to present a case of atypical manifestation of this rare disease, both due to clinical and epidemiological aspects.

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Section: Discussionmentioning

confidence: 50%

Cutaneous Plasmacytosis: Diagnostic and Therapeutic Challenge in a Patient with an Atypical Presentation

Amorim

Rosa

Buratto

et al. 2021

SPDV

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“… 12 Recent reports of low-dose thalidomide, narrowband ultraviolet B therapy, mask-bath psoralen combined with ultraviolet A, and intralesional corticosteroid injections have shown improvement in cutaneous plasmacytosis. 13 , 14 , 15 , 16 …”

Section: Discussionmentioning

confidence: 99%

Cutaneous plasmacytosis resembling pityriasis rosea in a 66-year-old white woman: A rare disease presenting in an unusual patient demographic

et al. 2017

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“…That is, do the lesions arise as a reaction of plasma cells, or are these lesions neoplastic? Few treatment approaches beyond the use of topical steroids have been tried [14] ; however, 2 recent studies have shown good results with thalidomide [15] and the use of narrowband ultraviolet B irradiation therapy [16] .…”

Section: Introductionmentioning

confidence: 99%

Characterization of Cutaneous Plasmacytosis at Different Disease Stages

Hsiao

Wu²

2016

Dermatology

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Background/Aims: Cutaneous plasmacytosis is rare and still not well understood. A retrospective study was made of 9 Chinese patients with 1- to 15-year histories of biopsy-proven cutaneous plasmacytosis diagnosed between 2003 and 2015. Methods: Patient records and archival photographs helped establish the pattern and duration of skin lesions, and skin biopsy specimens provided additional data. Results: The mean age at diagnosis was 46.4 years. Two patients had lesions within 1 year of developing the disease, and 4 had lesions lasting longer than 5 years. One patient had lymphadenopathy of the neck that was later determined to be Castleman disease. Three patients had elevated IgG4 levels; only 2 had increased IgG4+ cells in skin tissues. Flexural accentuation was prominent. Four patients had elevated IgG levels, and 1, with an IgG level >5,000 mg/dL, developed systemic plasmacytosis (later confirmed as Castleman disease). The level of IgG4 subclass was related to disease duration, whereas IgG4+ plasma cells in tissues seemed irrelevant. Conclusion: Routine laboratory tests, especially measurement of IgG4 levels, may be useful for following patients with cutaneous plasmacytosis. Because of the retrospective nature of our study, we could only evaluate the results of a single IgG4 test for each patient, but the results pointed to cutaneous plasmacytosis in all 9 patients, who had different stages of the disease. Serial skin biopsies may also be helpful for gauging disease progress. Although IgG4-related disease was not established in any of these patients, long-term follow-up is warranted for all patients.

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Cutaneous plasmacytosis successfully treated with narrowband ultraviolet B irradiation therapy

Cited by 7 publications

References 5 publications

Cutaneous Plasmacytosis: Diagnostic and Therapeutic Challenge in a Patient with an Atypical Presentation

Cutaneous Plasmacytosis: Diagnostic and Therapeutic Challenge in a Patient with an Atypical Presentation

Cutaneous plasmacytosis resembling pityriasis rosea in a 66-year-old white woman: A rare disease presenting in an unusual patient demographic

Characterization of Cutaneous Plasmacytosis at Different Disease Stages

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