Cutaneous plexiform lesions

Abbas, Ossama; Bhawan, Jag

doi:10.1111/j.1600-0560.2010.01529.x

Cited by 22 publications

(17 citation statements)

References 42 publications

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“…At birth, PNF may be only accompanied by slight symptoms, but the tumor will gradually grow and extend with the ages, and severe disfigurement and substantial loss of function will appear, which frequently leads to patient's social withdrawal. 9 …”

Section: Discussionmentioning

confidence: 99%

Initial Exploration on Temporal Branch of Facial Nerve Function Preservation in Plexiform Neurofibroma Resection

Bogari

Tan

et al. 2016

Journal of Craniofacial Surgery

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Background:Large temporal plexiform neurofibroma (PNF) is an irritating problem that causes facial disfigurement. Surgical resection of PNF is the only effective way to remove the tumor as well as to improve the patient's facial appearance. However, temporal branch of the facial nerve (TBFN) in the tumor is prone to be destroyed during PNF removal. Thus, TBFN palsy is the inevitable complication after surgery and might induce other malformation and dysfunction. Therefore, the aim of this study is to reconstruct a nearly normal face contour while preserving the facial nerve function.Purpose:Selective PNF removal technique was designed to protect TBFN during PNF lesions resection in our patients.Methods:From May 2011 to June 2015, the authors had 10 patients who suffered from PNF in the temporal region with facial disfigurement and underwent selective PNF removal to correct the facial disfigurement while preserving TBFN as well.Result:All patients obtained the improvement of facial appearance after surgery. The temporal PNF was removed and the TBFN function successfully maintained. Plexiform neurofibroma recurrence has not been relapsed during 6 to 49 months’ follow-up.Conclusions:In our initial exploration, TBFN function maintenance and facial appearance improvement can be achieved simultaneously by using PNF-selective removal surgery technique.

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Section: Discussionmentioning

confidence: 99%

Initial Exploration on Temporal Branch of Facial Nerve Function Preservation in Plexiform Neurofibroma Resection

Bogari

Tan

et al. 2016

Journal of Craniofacial Surgery

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“…Concerning clinical features, our case might mimic plexiform neurofibroma, nevus sebaceous, or epidermal nevus occurring on the scalp. The plexiform variant of neurofibroma, considered to be pathognomonic of neurofibromatosis type 1 (NF1), is usually present at birth as a noncircumscribed baggy, thick, irregular, and pedunculated dermal and subcutaneous tumor, and may result in significant disfigurement and dysfunction 8 . It involves single or multiple nerve fascicles that often arise from the branches of major nerves and form a mass of tangled, rope-like structures 9 .…”

Section: Discussionmentioning

confidence: 99%

Folliculocystic and Collagen Hamartoma: A New Entity?

Kim

Park

et al. 2015

Ann Dermatol

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Folliculocystic and collagen hamartoma is a newly described complex hamartoma characterized by abundant collagen deposition, concentric perifollicular fibrosis, and keratin- filled infundibular cysts that are visible on histopathological examination. Here, we report the case of a 19-year-old Korean man who had large brownish infiltrated plaques with numerous follicular comedo-like openings and subcutaneous cystic masses on his right temporal scalp and ear since birth. Histopathological examination showed abundant collagen deposition in the dermis that extended up to the subcutaneous fat layer, multifocal infundibular cysts packed with keratin, and perifollicular inflammation and fibrosis. Hence, we describe a new type of hamartoma with folliculocystic and collagen components but without tuberous sclerosis.

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“…The absence of axonal and perineurial elements as well as reactivity for GFAP set this tumor apart from a ‘true’ neuroma . Because of both schwann cell growth and multifascicular configuration, this lesion is best classified as a plexiform schwannoma …”

Section: Discussionmentioning

confidence: 99%

“…In particular, it is well known that granular cell tumor links to schwann cells and often induces epithelial hyperplasia . A rare plexiform variant of granular cell tumor in the skin also exhibits varying degrees of distinct fascicular arrangement . To our knowledge, there has been no description of non‐granular cell fascicles with schwannian characteristics in oral granular cell tumors …”

Section: Discussionmentioning

confidence: 99%

Oral plexiform schwannoma with unusual epithelial induction

et al. 2015

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Rare epithelial structures in benign nerve sheath tumors are almost always glandular in appearance. We describe a case of intraoral plexiform schwannoma with concurrent squamous epithelial hyperplasia. The lesion occurred as a pigmented nodule on the gingiva of a 35-year-old woman with no systemic involvement. Histologically, unencapsulated, plexiform fascicular proliferations of schwann cells could be traced from the submucosa to the lamina propria, finally making direct contact with heavily pigmented, elongated rete ridges of the overlying epithelium. Also noted was a schwannian network centered on clustered odontogenic epithelial rests of mature squamous-type, the number and size of which had markedly increased. Impressive immunoprofiles of periepithelial neural microfascicles included the complete absence of axon and perineurium and the unexpected presence of endoneurial fibroblasts. The repertoire of epithelial changes was in a confined area with no extension beyond, supporting hyperplasia induction by an underlying/surrounding schwannoma.

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Cutaneous plexiform lesions

Cited by 22 publications

References 42 publications

Initial Exploration on Temporal Branch of Facial Nerve Function Preservation in Plexiform Neurofibroma Resection

Initial Exploration on Temporal Branch of Facial Nerve Function Preservation in Plexiform Neurofibroma Resection

Folliculocystic and Collagen Hamartoma: A New Entity?

Oral plexiform schwannoma with unusual epithelial induction

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