Cutaneous pseudolymphoma after patch test to gold sodium thiosulfate in two patients

Torrijos, Elisa Gómez; Relea‐Calatayud, Fernanda; Mateos, Juan L. Santiago‐Sánchez; Galindo-Bonilla, Pedro Ángel; Carmona-Rodríguez, M.

doi:10.1111/cod.13470

Cited by 4 publications

(6 citation statements)

References 7 publications

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“…Since CPLs may appear similar to cutaneous lymphomas, clinical information as well as molecular and histopathology data are important to make the final diagnosis. [34][35][36][37][38][39][40][41][42] The final diagnosis of CPL is supported by the absence of…”

Section: Discussionmentioning

confidence: 99%

“…Since CPLs may appear similar to cutaneous lymphomas, clinical information as well as molecular and histopathology data are important to make the final diagnosis 34–42 . The final diagnosis of CPL is supported by the absence of T‐cell receptor rearrangement, negative immunoglobulin heavy chain gene rearrangements, absence of plasma cell (mono‐) clonality, and polyclonal lambda and kappa light chains 3,33 …”

Section: Discussionmentioning

confidence: 99%

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Drug‐induced cutaneous pseudolymphoma: A systematic review of the literature

et al. 2022

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Drug‐induced cutaneous pseudolymphoma (CPL) is a common form of pseudolymphoma and there are numerous drugs associated with it. In this study, we performed a systematic review of the literature by searching PubMed/Medline and Embase databases to determine the most common drugs responsible for CPL and to define the demographic, clinical, histopathological and immunopathological characteristics of patients (updated on 30 December 2020). From 883 initially found articles, 56 studies (89 reported cases) were included. The mean age of patients was 54.4 ± 17.7 (ranging 8–86) years, and 46 (51.7%) were men. The median time interval between drug intake and CPL occurrence was 120 days (range 1–7300 days). The shortest median time interval between taking the drug and the onset of the disease was observed among patients taking antidepressants (60 days) (range 7–540) and the longest median time interval was observed in individuals using immunomodulators (300 days) (range 3–7300). The most‐reported drug categories causing CPL were anti‐hypertensives (17.9%), anticonvulsants (14.6%), monoclonal antibodies (13.4%) and antidepressants (11.2%). Moreover, the most common drugs were phenytoin (6.7%), amlodipine (5.6%), fluoxetine (5.6%) and carbamazepine (4.4%). Histopathological evaluation of 76 cases revealed 62 (81.5%) reports of T‐cell infiltrations. Furthermore, positive reports of CD4 (94.0%), CD8 (93.0%) and CD30 (87.5%) were noted. The lowest prevalence of CD30‐positive reports was observed among monoclonal antibodies. In conclusion, anti‐hypertensives, anti‐convulsants, monoclonal antibodies and anti‐depressants are the most common drugs responsible for CPL. It mostly presents in middle‐aged patients with almost no gender difference as pruritic papules, nodules and plaques.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Drug‐induced cutaneous pseudolymphoma: A systematic review of the literature

et al. 2022

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“…Previously recorded cases of this condition are summarised in Table 1. [2][3][4] The present case highlights two pseudolymphomatous lesions after contact with two different gold sodium thiosulfate patches on the same patient.…”

Section: Observation Lettermentioning

confidence: 69%

“…Clinical reports of the latter are scarce. [2][3][4] Thus, this report highlights a case of pseudolymphoma after patch testing to gold sodium thiosulphate and performs a literature review of previously described cases.…”

Section: Sirmentioning

confidence: 99%

Pseudolymphoma induced by gold after patch testing: Dermoscopic features

Castillo

Menéndez-Parrón

Martinez-Aracil

et al. 2023

IJDVL

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“…We found 10 other cases of patch test‐induced pseudolymphomas with four allergens implicated: gold sodium thiosulfate (7/10), 3–7 minoxidil (2/10), 8,9 and only one case induced by methacrylates 10 . While all cases involved one single allergen, the latter involved both HEMA and HPMA.…”

Section: Discussionmentioning

confidence: 99%