Cutting-edge development in dendritic polymeric materials for biomedical and energy applications

Thalji, Mohammad R.; Amin, Amal; Ali, Gomaa A. M.

doi:10.1016/j.eurpolymj.2021.110770

Cited by 41 publications

(8 citation statements)

References 183 publications

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“…Aside from that, it provides a more straightforward approach since certain sugar-containing monomers prefer to self-polymerize during the purification process. In part because of its flexibility, versatility, and excellent chemical performance under mild conditions, the "Click" synthesis strategy, which includes reactions such as copper-catalyzed azide-alkyne-cycloaddition (CuAAC), Michael thiol addition, and radical thiol-ene reaction, is one of the most commonly used organic reactions for post-modification to prepare responsive glycopolymers [ 3 , 79 ]. Huang et al synthesized a diverse spectrum of block-type polypeptides by anionic ring-opening polymerization using a tertiary amine/LiBr starting system.…”

Section: Glycopolymer Synthesis Methodologiesmentioning

confidence: 99%

“…Recently, several researchers have demonstrated considerable interest in using many synthetic polymers in diverse applications [ 1 – 5 ]. Synthetic polymers can look like natural polymers, and natural polymers can be designed to appear like synthetic polymers [ 3 – 5 ]. Polymer structures can now be more precisely controlled because of breakthroughs in newly found technologies, allowing researchers to develop custom multifunctional materials with exact topologies [ 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

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Glycopolymer-Based Materials: Synthesis, Properties, and Biosensing Applications

et al. 2022

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Glycopolymer materials have emerged as a significant biopolymer class that has piqued the scientific community's attention due to their potential applications. Recently, they have been found to be a unique synthetic biomaterial; glycopolymer materials have also been used for various applications, including direct therapeutic methods, medical adhesives, drug/gene delivery systems, and biosensor applications. Therefore, for the next stage of biomaterial research, it is essential to understand current breakthroughs in glycopolymer-based materials research. This review discusses the most widely utilized synthetic methodologies for glycopolymer-based materials, their properties based on structure–function interactions, and the significance of these materials in biosensing applications, among other topics. When creating glycopolymer materials, contemporary polymerization methods allow precise control over molecular weight, molecular weight distribution, chemical activity, and polymer architecture. This review concludes with a discussion of the challenges and complexities of glycopolymer-based biosensors, in addition to their potential applications in the future. Graphical Abstract

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Section: Glycopolymer Synthesis Methodologiesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Glycopolymer-Based Materials: Synthesis, Properties, and Biosensing Applications

et al. 2022

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“…One of the main potential applications of STOBA materials is in portable electronics [55]. LIBs are commonly used in portable electronics such as smartphones, laptops, and tablets given their high energy density and long-lasting performance.…”

Section: Portable Electronics Evs and Renewable Energy Storage Systemsmentioning

confidence: 99%

Critical Review on High-Safety Lithium-Ion Batteries Modified by Self-Terminated Oligomers with Hyperbranched Architectures

Mohanty,

Hung,

Hsieh

et al. 2024

Batteries

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In recent years, the evolution of lithium-ion batteries (LIB) has been propelled by the growing demand for energy storage systems that are lightweight, have high energy density, and are long-lasting. This review article examines the use of self-terminated oligomers with hyperbranched architecture (STOBA) as a key electrode additive for the superior performance of LIBs. STOBA has been found to have excellent electrochemical properties, including high specific capacity, low impedance, and good cycling stability when used as an additive in electrode materials. The article discusses the process of synthesis and characterization of STOBA materials, including their potential applications in LIBs as electrode material additives. The article also discusses current research on the optimization of STOBA materials for LIBs, including the use of different solvents, monomers, and initiators. Overall, the review concludes that STOBA materials possess huge potential as a next-generation additive for LIB safety.

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“…Owing to their significance in clinical applications, as well as biology, these polymers have been widely utilized in different kinds of therapeutic areas, including allergies, antiviral drugs, the central nervous system, antimicrobials, cancer, and analgesia. 57 Dendritic polymers have potential applications in the treatment of cirrhosis. Graphite nanostars associated with polyamidoamine generation 5 dendritic polymers were created by Melgar-Lesmes et al 58 to facilitate the plasmatic transport of collagenase metalloproteinase 11 to inflammatory macrophages in cirrhotic livers, and they showed that the polymers reduced liver fibrosis and inflammatory macrophage accumulation.…”

Section: B Dendritic Polymersmentioning

confidence: 99%

Nanodrug delivery materials for digestive system diseases

Yang,

Zeng,

Zhuang

et al. 2024

APL Materials

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Digestive system diseases, such as gastritis, gastric ulcers, chronic liver disease, inflammatory bowel disease (IBD), and colorectal cancer, represent a major group of diseases that have high morbidity and death rates worldwide. Their incidence continues to rise owing to factors such as dietary structure changes, accelerated lifestyles, increased environmental pollution, and population aging. Despite the rapid development of the medical technology, the treatment of digestive diseases still faces many challenges, such as addressing drug-resistant Helicobacter pylori infections, treating IBD, and improving the efficacy of advanced gastrointestinal tumor therapies. Fortunately, the emergence of drug-releasing materials has provided new insights that can be used in the treatment of digestive disorders. Drug-releasing materials are a category of specially designed carriers or systems capable of carrying drugs and controlling their release at specific time intervals on demand to achieve the desired therapeutic effect. This article reviews recent research progress of drug-releasing materials used to diagnose and treat digestive disorders. First, the limitations of traditional oral drug delivery methods, such as low bioavailability and nonspecific distribution, are discussed. Second, different types of drug-releasing materials, such as liposomes, dendritic polymers, micelles, nanogels, inorganic nanoparticles, and extracellular vesicles, along with their advantages in terms of improved drug stability, biocompatibility, targeting, and controlled release, are outlined. In addition, the application strategies and preclinical findings of various drug release materials for different digestive disorders are discussed in detail. This Review could help researchers explore more advanced nanomaterials for personalized treatment of drug delivery for digestive disorders.

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Cutting-edge development in dendritic polymeric materials for biomedical and energy applications

Cited by 41 publications

References 183 publications

Glycopolymer-Based Materials: Synthesis, Properties, and Biosensing Applications

Glycopolymer-Based Materials: Synthesis, Properties, and Biosensing Applications

Critical Review on High-Safety Lithium-Ion Batteries Modified by Self-Terminated Oligomers with Hyperbranched Architectures

Nanodrug delivery materials for digestive system diseases

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