TiCN coatings of the same chemical compositions were deposited on HW/K05-K20 cemented carbide inserts via physical (PVD) and medium temperature chemical vapor deposition (MTCVD) techniques. Nano-indentations coupled with appropriate FEM simulations were used for characterizing the film and substrate mechanical properties. Furthermore, uncoated cemented carbide substrates were annealed in vacuum at temperatures and durations corresponding to the related ones during the PVD and MTCVD process for recording the effect of the deposition temperature and duration on the substrate strength properties. Perpendicular and inclined impact tests at various loads were performed for checking the coating fatigue endurance and adhesion respectively. These material data were considered in FEM supported calculations for predicting the developed stress fields in the cutting edge during turning cast iron GG30 using the PVD and MTCVD TiCN coated inserts. According to the obtained result, both coatings possess the same stress-strain properties. Hereupon, the MTCVD coatings are characterized comparably to PVD ones by improved fatigue properties and adhesion strength. Although these properties contribute to an increased tool life in finishing turning, the significant reduction of the substrate strength properties, due to the elevated temperature during the MTCVD process, results in a premature coating failure and a consequent intensive wear evolution in roughing.