Cutting the edge of idiopathic recurrent orbital myositis

Abstract

<jats:title>Abstract</jats:title><jats:p>The spectrum of orbital inflammatory diseases ranges broadly from specific diseases as connective tissue disorders, thyroid ophthalmopathy to non-specific inflammations, which may involve one or multiple structures of the orbit and/ or the surrounding sinus. Idiopathic orbital myositis (IOM) may be a localized process or it can be secondary to systemic diseases. We report 4 patients affected by IOM; in all relapsing diplopia was the main complaint, associated with orbital pain in 3 and with abnormal visual evoked responses in 2. Computed tomography (CT), magnetic resonance imaging (MRI) supported the diagnosis revealing enlargement, altered signal intensity of affected muscles. Repeated MRI scans and extensive laboratory examinations comprising of the search for a remote malignacy, lymproliferative, connective tissue diseases, thyroid ophthalmopathy were necessary to confirm the diagnosis. Oral or/and intravenous steroids were main treatments; relapses often occurred when steroid was tapered down. Intravenous immuneglobulins and azathioprine was used in one refractory case</jats:p>

Medical and Surgical Treatment in Pediatric Orbital Myositis Associated with Coxsackie Virus

“…It is not clear whether this occurred due to some potential for local dissemination of the inflammatory process or whether the inflammatory response in the LE medial rectus was deferred by any defensive mechanism. Asymmetric disease has been reported in the idiopathic type [ 9 ], but the reasons behind asymmetric and delayed onset disease in one eye assuming a systemic infectious aetiology are unclear. Like previous authors, we suggest that an aggressive and early disease therapy might be beneficial [ 2 ].…”