Cuttlebone: Characterisation, application and development of biomimetic materials

Cadman, Joseph; Zhou, Shiwei; Chen, Yuhang; Li, Qing

doi:10.1016/s1672-6529(11)60132-7

Cited by 85 publications

(54 citation statements)

References 38 publications

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“…Indeed, if the fish rises in the sea, the swim bladder will expand and tend to push it still higher, whereas if it goes deeper in the sea the swim bladder will be compressed and the fish will tend to sink more and more quickly [182]. To accomplish these functional and highly sophisticated requirements, the high porosity of CB enables cuttlefish maintaining its neutral buoyancy at a higher depth and at the same time retain enough stiffness and strength to prevent sever distortion or crushing under high hydrostatic pressures in deep water [180,183,184]. Dorsal shield and lamellar matrix represent the two main components of CB ( Figure 9).…”

Section: Cuttlefish Bonementioning

confidence: 99%

“…The dorsal shield is highly dense and provides a rigid substrate for protecting the development of the lamellar matrix. On the other hand, the lamellar matrix has a high porosity, approximately 93%, and also manages to withstand very high hydrostatic pressure [184]. The dorsal shield is a dense and tough cover that overlays the lamellar matrix and seals off the separated chambers.…”

Section: Cuttlefish Bonementioning

confidence: 99%

“…The lamellar matrix is a layered, quasi-periodic microstructure constituted by lamellae separated by pillars [184] , which is able to resist external pressures of about 2.4 MPa [180]. The spacing of the lamellae varies between 200 and 600 µm along the CB [180], being dependent on the specie [186] Each chamber is supported by pillars that form channels with a high degree of interconnectivity, and a uniform width that progresses through the material along a sigmoidal path [184].…”

Section: Cuttlefish Bonementioning

confidence: 99%

“…The spacing of the lamellae varies between 200 and 600 µm along the CB [180], being dependent on the specie [186] Each chamber is supported by pillars that form channels with a high degree of interconnectivity, and a uniform width that progresses through the material along a sigmoidal path [184]. Its unique macroporous architecture with approximately 93% of porosity is mainly composed of aragonite, which is a crystallized form of CaCO3.…”

Section: Cuttlefish Bonementioning

confidence: 99%

“…Its unique macroporous architecture with approximately 93% of porosity is mainly composed of aragonite, which is a crystallized form of CaCO3. This inorganic structure is enveloped in a thin layer of organic material composed primary of -chitin that represents between 3 and 4.5% of the lamellar matrix weight [180,184,187]. The presence of -chitin is associated with initiation, organization and inhibition of the inorganic matrix mineralization [180,187].…”

Section: Cuttlefish Bonementioning

confidence: 99%

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Synthetic and Marine-Derived Porous Bone Graft Substitutes

Neto¹,

Ferreira²

2018

Preprint

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Bone is a dynamic tissue with the capacity of repair and regeneration in specific conditions. Nevertheless, due to the increased incidence of bone disorders, the need of bone grafts has been growing over the past decades and the development of a bone graft with optimal properties remains a clinical challenge. This review addresses the bone properties (morphology, composition and their repair and regeneration capacity) and then is focused on the potential strategies for bone repair and regeneration. It describes the requirements for designing a suitable scaffold material, types of materials (polymers, ceramics and composites) and techniques to obtain the porous structures (additive manufacturing techniques/robocasting or derived from marine skeletons) for bone tissue engineering applications. The main objective of this review is to gather the knowledge on the materials and methods for the production of scaffolds for bone tissue engineering and highlight that natural materials, namely the marine skeletons represent a promising alternative.

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Section: Cuttlefish Bonementioning

confidence: 99%

Section: Cuttlefish Bonementioning

confidence: 99%

Section: Cuttlefish Bonementioning

confidence: 99%

Section: Cuttlefish Bonementioning

confidence: 99%

Section: Cuttlefish Bonementioning

confidence: 99%

See 3 more Smart Citations

Synthetic and Marine-Derived Porous Bone Graft Substitutes

Neto¹,

Ferreira²

2018

Preprint

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Thermomechanical Analysis of a Bio‐Inspired Lightweight Multifunctional Structure

et al. 2020

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Cuttlebone constitutes the inner shell of a cuttlefish, and it has a highly porous chambered microstructure of about 93% porosity by volume. [1] Cuttlebone functions as a skeletal element and a rigid buoyancy tank, which allows the organism to control its overall density by regulating the gas/liquid ratio inside its porous structure. [2] As some cuttlefish can live up to 600 m deep in the ocean, the partially gas-filled cuttlebone is required to withstand extreme compressive loading from the water pressure (up to 60 atm). [3,4] Previous studies have suggested that cuttlebone's remarkable damage tolerance and high stiffness can be attributed to its characteristic "wall-septa" internal morphology. [5] Several previous studies on cuttlebone have explored its potential applications by exploiting its chemical, structural, and mechanical characteristics as a natural cellular material. For example, cuttlebone itself can be used as a filler in natural rubber [6] and acrylic bone cement, [7] the mechanical properties of which are comparable to commercial products. In addition, a poly coated hydroxyapatite scaffold derived from cuttlebone through a hydrothermal transformation process was shown to exhibit enhanced mechanical properties and is a good candidate for bone tissue engineering applications. [8-10] Previous research on bio-inspired structures based on cuttlebone has generally focused on structural applications, motivated by cuttlebone's low density and high strength. [1,4,11,12] Currently, little research has been carried out to explore the potential multifunctional performance of cuttleboneinspired structures. In particular, the "wall-septa" morphology of cuttlebone resembles the arrangement of a plate and pins in a typical pin-fin heat sink [13,14] as well as the sandwich structure used in an integrated thermal protection system (ITPS) for spacecraft vehicles. [15-17] The combination of high mechanical performance (stiffness and damage tolerance), low density, and pin-fin-like configuration motivates us to explore the potential thermomechanical applications of cuttlebone-inspired structures. In addition to computationally analyzing the mechanical performance of the cuttlebone structure based on high-resolution 3D structural reconstruction, this research systematically analyzes the feasibility of using cuttlebone as an inspiration for the design of novel lightweight multifunctional structures for thermal management applications, including an air-cooled heat sink for electronic devices and an ITPS for spacecraft vehicles. Regarding the air-cooled heat sink evaluation, devising effective thermal management methods for electronic components are becoming increasingly difficult due to the demand for higher performance and the continual miniaturization of electronic devices. Numerous studies have been conducted to analyze heat sinks with natural convection, including the effect of pin fin orientation and pressure drop on local heat transfer, [18-22] effective fin shape and height for maximum heat transfer, [23-25] and e...

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A 3D‐Printed Cuttlefish Bone Elastomeric Sponge Rapidly Controlling Noncompressible Hemorrhage

Zhang,

Wang,

Yuan

et al. 2023

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Developing a self‐expanding hemostatic sponge with high blood absorption and rapid shape recovery for noncompressible hemorrhage remains a challenge. In this study, a 3D‐printed cuttlefish bone elastomeric sponge (CBES) is fabricated, which combined ordered channels and porous structures, presented tunable mechanical strength, and shape memory potentials. The incorporation of cuttlefish bone powder (CBp) plays key roles in concentrating blood components, promoting aggregation of red blood cells and platelets, and activating platelets, which makes CBES show enhanced hemostatic performance compared with commercial gelatin sponges in vivo. Moreover, CBES promotes more histiocytic infiltration and neovascularization in the early stage of degradation than gelatin sponges, which is conducive to the regeneration and repair of injured tissue. To conclude, CBp loaded 3D‐printed elastomeric sponges can promote coagulation, present the potential to guide tissue healing, and broaden the hemostatic application of traditional Chinese medicine.

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Cuttlebone: Characterisation, application and development of biomimetic materials

Cited by 85 publications

References 38 publications

Synthetic and Marine-Derived Porous Bone Graft Substitutes

Synthetic and Marine-Derived Porous Bone Graft Substitutes

Thermomechanical Analysis of a Bio‐Inspired Lightweight Multifunctional Structure

A 3D‐Printed Cuttlefish Bone Elastomeric Sponge Rapidly Controlling Noncompressible Hemorrhage

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