Cyanobacteria blooms induce embryonic heart failure in an endangered fish species

Zi, Jinmei; Pan, Xiaofu; MacIsaac, Hugh J.; Yang, Jing; Xu, Runbing; Chen, Shanyuan; Xu, Chunju

doi:10.1016/j.aquatox.2017.11.007

Cited by 56 publications

(22 citation statements)

References 39 publications

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“…Under stressful conditions, metabolic changes are expected in response to different environmental variations and the development of tissue oedema, size and shape modification are effects previously reported for several aquatic organisms [56]. In the initial stage of fish development, these effects may compromise survival since larvae are more sensitive to toxic compounds in freshwater ecosystems [68,69,70,71,72,73].…”

Section: Discussionmentioning

confidence: 99%

Toxicity of Cyanopeptides from Two Microcystis Strains on Larval Development of Astyanax altiparanae

Fernandes

Gomes

Calado

et al. 2019

Toxins

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Absorption and accumulation of bioavailable cyanobacterial metabolites (including cyanotoxins) are likely in fish after senescence and the rupturing of cells during bloom episodes. We determined the toxicity of cyanopeptides identified from two strains of Microcystis (M. panniformis MIRS-04 and M. aeruginosa NPDC-01) in a freshwater tropical fish, Astyanax altiparanae (yellowtail tetra, lambari). Aqueous extracts of both Microcystis strains were prepared in order to simulate realistic fish exposure to these substances in a freshwater environment. Both strains were selected because previous assays evidenced the presence of microcystins (MCs) in MIRS-04 and lack of cyanotoxins in NPDC-01. Identification of cyanobacterial secondary metabolites was performed by LC-HR-QTOF-MS and quantification of the MC-LR was carried out by LC-QqQ-MS/MS. MIRS-04 produces the MCs MC-LR, MC-LY and MC-HilR as well as micropeptins B, 973, 959 and k139. NPCD-01 biosynthetizes microginins FR1, FR2/FR4 and SD-755, but does not produce MCs. Larval fish survival and changes in morphology were assessed for 96 h exposure to aqueous extracts of both strains at environmentally relevant concentrations from 0.1 to 0.5 mg (dry weight)/mL, corresponding to 0.15 to 0.74 μg/mL of MC-LR (considering dried amounts of MIRS-04 for comparison). Fish mortality increased with concentration and time of exposure for both strains of Microcystis. The frequencies of morphological abnormalities increased with concentration in both strains, and included abdominal and pericardial oedema, and spinal curvature. Results demonstrate that toxicity was not solely caused by MCs, other classes of cyanobacterial secondary metabolites contributed to the observed toxicity.

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Section: Discussionmentioning

confidence: 99%

Toxicity of Cyanopeptides from Two Microcystis Strains on Larval Development of Astyanax altiparanae

Fernandes

Gomes

Calado

et al. 2019

Toxins

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show abstract

“…Cyanobacteria can be a poor‐quality food resource for grazers due to low nutritional value or mucilaginous sheathing that poses high digestion resistance (DeMott and Tessier ; but see Perga et al ). Thus, increased cyanobacterial dominance could decrease negatively impact grazers and ultimately zooplanktivorous fish (Hansson et al ; Zi et al ). Additionally, N‐limiting conditions can favor the growth of toxin producing cyanobacteria which can lead to the development of HABs.…”

Section: Discussionmentioning

confidence: 99%

Nitrate, ammonium, and phosphorus drive seasonal nutrient limitation of chlorophytes, cyanobacteria, and diatoms in a hyper‐eutrophic reservoir

Andersen

Williamson

González

et al. 2019

Limnology & Oceanography

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Nitrogen (N) and phosphorus (P) inputs influence algal community structure and function. The rates and ratios of N and P supply, and different N forms (e.g., NO 3 and NH 4 ), from external loading and internal cycling can be highly seasonal. However, the interaction between seasonality in nutrient supply and algal nutrient limitation remains poorly understood. We examined seasonal variation in nutrient limitation and response to N form in a hypereutrophic reservoir that experiences elevated, but seasonal, nutrient inputs and ratios. External N and P loading is high in spring and declines in summer, when internal loading because more important, reducing loading N:P ratios. Watershed NO 3 dominates spring N supply, but internal NH 4 supply becomes important during summer. We quantified how phytoplankton groups (diatoms, chlorophytes, and cyanobacteria) are limited by N or P, and their N form preference (NH 4 vs. NO 3 ), with weekly experiments (May-October). Phytoplankton were P-limited in spring, transitioned to N limitation or colimitation (primary N) in summer, and returned to P limitation following fall turnover. Under N limitation (or colimitation), chlorophytes and cyanobacteria were more strongly stimulated by NH 4 whereas diatoms were often equally, or more strongly, stimulated by NO 3 addition. Cyanobacteria heterocyte development followed the onset of N-limiting conditions, with a several week lag time, but heterocyte production did not fully alleviate N-limitation. We show that phytoplankton groups vary seasonally in limiting nutrient and N form preference, suggesting that dual nutrient management strategies incorporating both N and P, and N form are needed to manage eutrophication.

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“…sp strains can produce the microcystin which is harmful to liver and kidney of human and induce neurological and skin diseases . Thus, algal blooms pose a potential risk to wild animals drink impaired water resources, and also affect the genetics and growth of fishes . Furthermore, cyanobacteria bloom and microcystin will impact the normal operation of water plants, increase the cost of water purification, and reduce water safety.…”

Section: Introductionmentioning

confidence: 99%

Growth Inhibition of Microcystis aeruginosa by Copper‐based MOFs: Performance and Physiological Effect on Algal Cells

Fan

Zheng

Chen

2018

Applied Organom Chemis

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The problem of cyanobacteria bloom occurring in the eutrophic water increases more serious and urgent needs to be solved. Based on the advantages of Metal-organic frameworks (MOFs), some reported studies have evaluated the inhibition effect of MOFs on algae. However, the influence of that on the physiological characteristics of algal cells has not been investigated thoroughly.In this study, Cu-MOF-74 was successfully synthesized by a facile hydrothermal method and was characterized by XRD and SEM. The growth inhibition of Microcystis aeruginosa were conducted to explore the effects of Cu-MOF-74 based on the physiology of algal cells to reveal algae inhibition mechanism. The results showed that the synthesized Cu-MOF-74 was a large needle-shaped crystal, and the size of the grain was 3-4.5 μm. 1 mg/L of Cu-MOF-74 has relatively excellent inhibitory effect on algae, which can achieve the removal efficiency of 75.5% within 120 hr. Besides, the content of chlorophyll a decreased by about 56%, the diminishing of chlorophyll a and phycobiliprotein concentration resulted in photosystem damage. In this process, ROS accumulated continually in algal cells with the slow release of metal ions Cu 2+ of Cu-MOF-74 which acts as a 'reservoir', then causing the oxidation loss, the reduction of SOD activity and the increase of CAT activity. The hydroxyl radical generated by Cu-MOF-74 caused lipid peroxidation. Thereby the situation above eventually resulted in the death of Microcystis aeruginosa and the concentration of extracellular organic matter increased. All the above, we think Cu-MOF-74 can inhibit the growth of algal cells through effecting on physiology and can be applied to control the cyanobacteria blooms.

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Cyanobacteria blooms induce embryonic heart failure in an endangered fish species

Cited by 56 publications

References 39 publications

Toxicity of Cyanopeptides from Two Microcystis Strains on Larval Development of Astyanax altiparanae

Toxicity of Cyanopeptides from Two Microcystis Strains on Larval Development of Astyanax altiparanae

Nitrate, ammonium, and phosphorus drive seasonal nutrient limitation of chlorophytes, cyanobacteria, and diatoms in a hyper‐eutrophic reservoir

Growth Inhibition of Microcystis aeruginosa by Copper‐based MOFs: Performance and Physiological Effect on Algal Cells

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