Cyanosis and Clipping: Noninfectious Aneurysm in a Patient with 22q11.2 Deletion Syndrome

Abstract

Noninfectious cerebral aneurysms are rare in patients with congenital cyanotic heart disease. We present a patient with DiGeorge/velocardiofacial syndrome with a complex congenital cyanotic heart disease with a ruptured anterior communicating artery aneurysm. The 10-year-old child was managed by surgical clipping of the aneurysm. Surgical challenges included prominent veins in the Sylvian fissure, difficulty in differentiating arterial and venous bleed, and anesthetic risks. The patient recovered without any neurological deficits. This is the first report of a patient with 22q11.2 deletion syndrome, with a noninfectious cerebral aneurysm.

Ruptured Middle Cerebral Artery Aneurysm in an Infant: Case Report and Literature Review

“…The following are some of the reasons why endovascular treatment is preferred: the difficulty of identifying the Sylvian fissure, distinguishing arteries from veins, the low volume of blood circulation, and the risk of anesthesia when compared to adults. 14 , 15 ) Furthermore, it is notable that children exhibit higher tolerance to vasospasm when compared to adults. This could be attributed to their augmented leptomeningeal circulation and cerebral blood flow.…”