Improving lateral branch development in young sweet cherry trees without reliance on pruning is a desirable component of tree training programs, especially for high-density systems. Applications of two proprietary formulations of 6-benzyladenine and gibberellins A4 and A7 (Promalin, Valent Biosciences, Walnut Creek, Calif.; and Perlan, Fine Americas, Walnut Creek, Calif.) to individual buds or intact bark of unpruned sweet cherry central leader shoots at green-tip had little effect on lateral shoot growth from buds or on distribution of new shoot growth along the treated leader shoots. Scoring, nicking, or notching cuts alone also had inconsistent effects on shoot development and distribution. In some trials, bud removal (or disbudding, removing every fourth bud on 1-year-old shoots) produced limited improvement of lateral shoot development and vertical distribution. Combining nicking, notching, scoring, or bark scraping with the application of cytokinin–gibberellic acid solution to the cut area greatly improved both number of shoots developed and the numbers originating from the lower portions of treated leader shoots. Removing the physical barrier to bioregulator product contact with active tissues was a primary factor in improving treatment efficacy.