Cycle scheduling with oral contraceptive pills in the GnRH antagonist protocol vs the long protocol: a randomized, controlled trial

GnRH-antagonist programming versus GnRH agonist protocol: a randomized trial

“…The most recent randomized controlled trial testing oral contraceptive pre-cycle exposure compared the long protocol to a GnRH-antagonist OCP-programmed cycle [4]. They reported no difference in embryological outcomes, clinical pregnancies and live birth rates and thus concluded it is a good option for cycle scheduling.…”

“…These have primarily involved oral contraceptives (OCP) pretreatment and luteal oral estrogen administration. Conflicting results regarding possible detrimental effects to cycle quality have been reported with OCP [2][3][4]. Luteal estrogen use was tested for its ability to affect follicular recruitment quality [5,6].…”

Early progesterone cessation after in vitro fertilization/intracytoplasmic sperm injection: a randomized, controlled trial

“…COH was performed as previously described (17). Briefly, patients received a starting dose of recombinant FSH (Puregon, Organon; or Gonal F, Serono) ranging from 200 to 225 IU and 0.25 mg GnRH antagonist ganirelix (Orgalutran, Organon) administered daily, introduced on day 5 or 6.…”

Assisted Reproduction

“…It does not appear, however, that low levels of estradiol are, in fact, detrimental to pregnancy rates in these IVF cycles. 164 When LH levels are too high, premature ovarian luteinization may occur. It is unclear whether LH is required for optimal ovarian stimulation as studies do not uniformly indicate that the addition of LH to ovarian stimulation improves pregnancy rates, though estradiol levels are higher.…”