2004
DOI: 10.1002/jhet.5570410601
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Cyclic 1,3‐diones and their derivatives—As versatile reactive intermediates in the syntheses of condensed fused ring heterocyles

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Cited by 20 publications
(5 citation statements)
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“…Cyclic 2-alkyl-1,3-alkanediones ( 7 , R = alkyl) constitute key synthetic building blocks for the construction of heterocycles, complex molecules, and natural products (Figure A). Two of the most prominent examples derived from these structural motifs are the Wieland–Miescher and Hajos–Parrish ketones, 3 and 4 , which represent crucial synthetic intermediates in strategies toward steroid and terpene natural products .…”
mentioning
confidence: 99%
“…Cyclic 2-alkyl-1,3-alkanediones ( 7 , R = alkyl) constitute key synthetic building blocks for the construction of heterocycles, complex molecules, and natural products (Figure A). Two of the most prominent examples derived from these structural motifs are the Wieland–Miescher and Hajos–Parrish ketones, 3 and 4 , which represent crucial synthetic intermediates in strategies toward steroid and terpene natural products .…”
mentioning
confidence: 99%
“…For over a century, cyclic 1,3-diketones have been known to form condensation products, including selfcondensation (Wislicenus, 1887). As a result of this property, they have found use as intermediates for condensed cyclization products (Sekhar, 2004;Kozlov & Gusak, 2006) that have themselves found use as antiemetic (Kuang et al, 1994) and anticancer (Heidelberger & Ansfield, 1963) drugs. The various arms extending from the central ring.…”
Section: Chemical Contextmentioning
confidence: 99%
“…Found: C,63.48;H,4.40;N,4.23. (Z)-5-(4-Benzyloxy-3-methoxybenzylidene)-2-thioxothiazolidine-4-one (11) ,4.23;N,3.92. Found: C,60.58;H,4.15;N,3. Anal. Calcd.…”
Section: Procedures For the Synthesis Of Thiazolidine-24-dione Motif mentioning
confidence: 99%
“…Various 1,3-thiazolidine derivatives have been reported for their diverse biological activities apart from synthetic interests [1][2][3][4]. Activities such as antibacterial [5], antiinflammatory, cardiovascular, hypoglycaemic, lipid lowering [6,7] and various others have been reported [8].…”
Section: Introductionmentioning
confidence: 99%