Cyclic variation of myocardial signal intensity in real-time myocardial perfusion imaging

Effects of ultrasound-targeted microbubble destruction on cardiac gene expression

“…During myocardial contrast echocardiography (MCE), microbubbles are destroyed at defined time points in the myocardial vasculature. During some applications, the destruction is facilitated by intermittent use of high mechanical index US, either in a triggered mode with increasing time intervals (Wei et al 2001;Villanueva et al 2001) or manually after complete opacification of the myocardium in a real-time mode (Bekeredjian et al 2002;Masugata et al 2001).…”

Quantification Methods in Contrast Echocardiography

“…This high-frequency variation has been analyzed in some reports, although systolic/diastolic ratios do not seem to be related to regional functional parameters [27,28]. For this reason, to obtain a correct fitting when using real-time imaging, it is very convenient to perform a previous low-pass filtering of the curve.…”

Myocardial Perfusion Imaging During Stress Using Contrast Echocardiography

“…During stress, increased myocardial blood flow should mean that an individual segment will reperfuse more quickly than at rest. There is a naturally occurring cyclic variation in the myocardial contrast effect [ 17,18] and this, together with segmental motion, can make interpretation of these images in a real-time mode difficult. Therefore, it is often easier to use a triggered capture mode on the ultrasound system, so that only end-systolic or end-diastolic frames are stored.…”