Cyclic Voltammetry and Electrochemical Impedance Spectroscopy of Partially Reduced Graphene Oxide - PEDOT:PSS Transducer for Biochemical Sensing

Abstract

Electron-transfer kinetics and impedance at the electrode-solution interface affect biosensor performance. Cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) are used to understand the reversibility of electron transfer and impedance at the electrode-solution interface, respectively. Effective surface areas calculated based on the Randles-Sevcik equation for a bare screen-printed carbon electrode (SPCE), a graphene oxide (GO)-poly (3,4-ethylenedioxythiophene):polystyrenesulfonic acid (PEDOT:PSS)-modified electrode (GO-PEDOT:PSS/SPCE), a Engineering main heading: Conducting polymers

Structural electrochemistry of poly(3,4-ethylenedioxythiophene) and its applicability as simultaneous sensor of environmental surroundings: self-sensing electrical, thermal, and chemical working conditions

“…The working electrode was a glassy carbon electrode coated with PEDOT, while the reference electrode was an Ag/AgCl (3 M) electrode, and the counter electrode was a platinum wire. 43 The potential was cycled between −0.6 and 0.8 V in a 1 M aq. NaCl solution, at a scan rate of 25 mV s −1 .…”

Electrochemical and electrophysiological considerations for clinical high channel count neural interfaces

“…Typically, the first irreversible reaction observed is the electrolysis of water. 81 , 82 Cyclic voltammetry (CV) measurements, in which a voltage excursion is applied on the electrode and the resultant current is sampled, are typically carried out to establish the electrolysis window for the given material. 83 To establish the CIC, a current-clamped square wave stimulation can be applied at the electrode, and the resulting excursion potential on the electrode can be measured.…”

Combining PEDOT:PSS Polymer Coating with Metallic 3D Nanowires Electrodes to Achieve High Electrochemical Performances for Neuronal Interfacing Applications

“…[34,35] Consequently, 3D-electrode performances must be improved through surface modification at the nanoscale to enable precise recordings and maximum charge transfer, as well as keeping the optimal designs of the electrodes, while being minimally troublesome to the tissue. Metallic and organic coatings on the electrode active site, such as IrOx, [36][37][38][39] Pt black, [40] graphene oxide, [41,42] carbon nanotubes, [43] or conductive polymers such as Poly (3,4-ethylenedioxythiophene) (PEDOT) [7,10,[44][45][46] have been gaining considerable interest for interfacing with neurons as they can improve charge transfer and reduce the electrode impedance. PEDOT:PSS possesses well-known properties such as high conductivity, biocompatibility, and excellent stability.…”