Cyclic Voltammetry, Kinetics, Thermodynamic and Molecular Docking Parameters for the Interaction of Nickel Chloride with Diphenylthiocarbazone

Abstract

The electrochemical behavior of nickel chloride in citric acid aqueous solution (0.1M) in the presence of potassium ferrioxalate K3Fe(Oxalate)3 (KFOx) as moderator sensor and by the use of gold working electrode (GWE) was studied. Since nickel ions do not show any peaks in acidic media, but after adding potassium ferrioxalate K3Fe(Oxalate)3 (KFOx) as a sensor, two redox peaks of nickel ions were obtained. (KFOx) sensor indicating the appearance of nickel ion peaks. Two redox couples of waves were obtained attributed to [Ni(II)-Ox-Fe(III)]/[Ni(III)-Ox-Fe(III)]and[Ni(II)-Ox-Fe(III)] /[Ni(II)-Ox-Fe(II)]. The cyclic voltammetry for NiCl2 and its interaction with diphenylthiocarbazone, dithizone was studies at three different temperatures, 293.15, 303.15 and 313.15K. Different thermodynamic and kinetic parameters of interaction of nickel ions with dithizone were evaluated from the cyclic voltammograms. The estimated cyclic voltammetry values were discussed. Molecular docking was carried out to predict the binding between diphenylthiocabazone, dithizone ligand with the receptor of human liver cancer (3cmf). We can propose that interaction between the 3cmf receptors and the ligand is possible.

Determination of calcium in water samples by using Au-electrode in HCl solution in the absence and presence of a crystal violet and environmental studies

“…Ca(Crystal violet)4(HO -)2 4+ + HO -+ 4eelectro oxidation Ca(Crystal violet)4(HO -)(O -)  The voltammogram contains many evaluated data and R 2 have approximately constant value [15][16][17][18]. Most of the statistics in Table 1 are reduced by an increase in the ligand concentration.…”

Effect of indomethacin on the electrical conductance and electrochemical voltammetry of copper chloride in methanol, ethanol, and their binary mixture with water

“…As the working electrode's potential changes linearly over time during cyclic voltammetry, oxidation and reduction reactions in the system take place. The resulting current is measured, and a cyclic voltammogram is obtained, which plots the current response of an electrochemical system as a function of the applied potential [ [13] , [14] , [15] ]. By analyzing the shape and characteristics of the resulting cyclic voltammogram, information about the redox behavior of metal ions can be obtained; this includes the identification of oxidation and reduction peaks, which correspond to specific redox processes.…”