Cyclodextrin‐based molecularly imprinted polymers for the efficient recognition of pyrethroids in aqueous media

Abstract

Recent years have witnessed growing applications of the molecular imprinting technique for the detection of pesticide residues in environmental and food samples. In this study, molecularly imprinted polymers (MIPs) for pyrethroids, a class of popular insecticides, were synthesized by the crosslinking of β‐cyclodextrin (β‐CD) with 1,6‐hexamethylene diisocyanate (HMDI) or toluene‐2,4‐diisocyanate (TDI) in dimethyl sulfoxide, with lambda‐cyhalothrin (LCT) as a model template. Equilibrium batch‐rebinding tests were operated in different aqueous solutions. The results indicate that MIP prepared with TDI (MIP–TDI) possessed a much greater binding activity to LCT than MIP based on HMDI (MIP–HMDI), and MIP–TDI displayed a remarkably specific binding to LCT (with an imprinting factor of around 3) in an acetonitrile/water (4:7 v/v) mixture. The adsorption of LCT by MIP–TDI reached equilibrium after 3 h; this demonstrated comparatively rapid adsorption kinetics. Also, MIP–TDI could be regenerated eight times at least; this implied that the robust β‐CD polymer has the potential for practical applications. Furthermore, a cross‐selectivity study indicated that the high adsorption of LCT and its analogues by MIP–TDI in aqueous media must have been ascribed to the cooperative effects of CD inclusion interaction and stereoshape memory. This study paved the way for the use of β‐CD as a functional monomer for preparing smart artificial receptors for the efficient recognition of pyrethroids under aqueous conditions. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013

Selective extraction of fungicide carbendazim in fruits using β‐cyclodextrin based molecularly imprinted polymers

“…The surface of the MIPs was porous having embedded cavities after the removal of the template while the NIPs surface was non‐porous. The presence of the cavities in MIPs confirmed the successful completion of the imprinting process .…”

Synthesis and characterization of molecularly imprinted polymer embedded composite cryogel discs: application for the selective extraction of cypermethrins from aqueous samples prior to GC-MS analysis

“…As shown in Table 3, the bound amount of aand b-CYP for MIP composite cryogel discs was higher than that of the other two pesticides, suggesting that template molecule had a relatively higher affinity for the imprinted polymer than its analogues. 45 As shown in Fig.…”

“…35,42,43 Thus, keeping in mind the double benets of imprinted composite cryogels aand b-CYP imprinted poly(hydroxyethyl methacrylate-N-methacryloyl-L-phenylalanine) monoliths were synthesized separately, washed, crushed, sieved and nally embedded in cryogel membrane. The cyclodextrin based MIP was reported by Guo et al, 45 for selective extraction of pyrethroid pesticides from aqueous media. MAPA was chosen as functional monomer because additional interactions were expected between phenyl groups of MAPA and CYP.…”

A microtitre chemiluminescence sensor for detection of pyrethroids based on dual‐dummy‐template molecularly imprinted polymer and computational simulation

“…Therefore, there have been many articles reporting the use of MIPs as recognition elements to develop various analytical methods for the detection of different analytes, such as electrochemical sensor, pseudoimmunoassay and flow‐injection CL method . Previously, there have been some papers reporting the synthesis of MIPs for PYs, but most of the reported MIPs are used as absorbents to develop different sample extraction methods, and only two of these have been used as recognition reagents to prepare CL methods for detection of PYs …”