Cyclodextrin Modified Carbon Paste Based Electrodes as Sensors for the Determination of Carcinogenic Polycyclic Aromatic Amines

Abstract

Voltammetric properties and possibility of the determination of carcinogenic aminoderivatives of polycyclic aromatic hydrocarbons, namely 1-and 2-aminonaphthalene and 2-aminobiphenyl, have been investigated. Carbon paste electrodes (CPE) modified with monomeric a-, b-or g-cyclodextrin and carbon-based screen-printed electrodes (SPE) surface-modified with a thin film of b-cyclodextrin (b-CDP) or carboxymethylated b-cyclodextrin (b-CDPA) condensation polymer were used for that purpose as simple electrochemical biosensors. Analytical procedure for the DPV determination of tested amines using these biosensors was proposed. Linear calibration plots within the concentration range of 2 Â 10 À8 ± 2 Â 10 À7 mol dm À3 and 2 Â 10 À7 ± 1 Â 10 À6 mol dm À3 with limits of quantification of the order of 10 À9 mol dm À3 were obtained for the modified CPE and modified SPE.

Eletrodos de pasta de carbono modificados com ácidos húmicos: estudo e determinação de metais em meio aquoso

“…Dessa forma, vários trabalhos vêm sendo publicados em revistas especializadas, em que os autores relatam diferentes tipos de eletrodos utilizados na quantificação de espécies eletroativas [3][4][5][6][7] . Podese destacar entre eles os eletrodos de pasta de carbono (EPCs) [8][9][10][11][12] . O primeiro EPC foi desenvolvido por Adams, com intuito de substituir o eletrodo gotejante de mercúrio.…”

“…Em 1965, Kuwana e Schultz publicaram um artigo envolvendo EPC e compostos orgâni-cos 17 . Assim, sendo os pioneiros na área, abriram caminho para novos pesquisadores utilizarem substâncias eletroquimicamente ativas como modificadores 8 .…”

“…Assim, pode-se obter o valor da constante de estabilidade pela equação: (8) Para complexos com número de coordenação maior que 1 a Equação 8 pode ser adaptada 42 .…”

A New Electrochemical DNA Sensor for Sequence-Specific DNA Detection Based on DNA-functionalized CdS Nanoparticle

“…methods. [1][2][3][4][5][6] The electrochemical DNA sensing technology has received particular attention mostly due to its high sensitivity, selectivity and easy operation with simple instrumentations. The DNA recognition event can be detected using different strategies, including intrinsic electroactivity of the nucleic acid, enzyme labels, DNA duplex intercalators, electroactive markers, and metal nanoparticles/quantum dots.…”

An E-DNA Sensor for Sequence-Specific DNA detection

“…methods. [1][2][3][4][5][6] The electrochemical DNA sensing technology has received particular attention mostly due to its high sensitivity, selectivity and easy operation with simple instrumentations. The DNA recognition event can be detected using different strategies, including intrinsic electroactivity of the nucleic acid, enzyme labels, DNA duplex intercalators, electroactive markers, and metal nanoparticles/quantum dots.…”