Cyclodextrin subject-object recognition-based aptamer sensor for sensitive and selective detection of tetracycline

Wu, Yaohui; Bi, Hao; Ge, Ning; Xu, Zhenggang; Liu, Gao-Qiang; Wang, Yonghong; Zhao, Yunlin

doi:10.1007/s10008-020-04751-7

Cited by 14 publications

(5 citation statements)

References 39 publications

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“…The magnetic nanoparticles are functionalized with amine groups and then coupled with the CDs through the reaction of the NH 2 and CHO groups, combined with the enzyme and cast onto a magnetic substrate. The ferrocene/β-CD inclusion complex has also been applied in the assembly of aptamer-based sensors [178][179][180]. Aptamers are single-stranded RNA or DNA oligonucleotides and they can bind with high affinity and specificity to their target molecules.…”

Section: Cyclodextrin-based Biosensorsmentioning

confidence: 99%

“…Provided a conducting pathway exists, these interactions can be converted into an electrochemical signal. This strategy was used by Wu et al [179] and Xue et al [178] to form electrochemical aptasensors for the detection of tetracycline and thrombin, respectively. In both cases, a thiolated β-CD was attached to a gold substrate and the aptamer was labeled with ferrocene, enabling the formation of an inclusion complex between the ferrocene and β-CD, while anchoring the aptamer to the surface.…”

Section: Cyclodextrin-based Biosensorsmentioning

confidence: 99%

“…In both cases, a thiolated β-CD was attached to a gold substrate and the aptamer was labeled with ferrocene, enabling the formation of an inclusion complex between the ferrocene and β-CD, while anchoring the aptamer to the surface. On recognizing the target analyte, the aptamer changes its configurations moving the ferrocene/aptamer/target complex away from the surface and reducing the electrochemical signal [179], or closer to the surface to increase the signal [178].…”

Section: Cyclodextrin-based Biosensorsmentioning

confidence: 99%

“…The ferrocene/β-CD inclusion complex has also been applied in the assembly of aptamer-based sensors [178][179][180]. Aptamers are single-stranded RNA or DNA oligonucleotides and they can bind with high affinity and specificity to their target molecules.…”

Section: Enantioselective Cyclodextrin-based Electrochemical Sensorsmentioning

confidence: 99%

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Cyclodextrins as Supramolecular Recognition Systems: Applications in the Fabrication of Electrochemical Sensors

et al. 2021

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Supramolecular chemistry, although focused mainly on noncovalent intermolecular and intramolecular interactions, which are considerably weaker than covalent interactions, can be employed to fabricate sensors with a remarkable affinity for a target analyte. In this review the development of cyclodextrin-based electrochemical sensors is described and discussed. Following a short introduction to the general properties of cyclodextrins and their ability to form inclusion complexes, the cyclodextrin-based sensors are introduced. This includes the combination of cyclodextrins with reduced graphene oxide, carbon nanotubes, conducting polymers, enzymes and aptamers, and electropolymerized cyclodextrin films. The applications of these materials as chiral recognition agents and biosensors and in the electrochemical detection of environmental contaminants, biomolecules and amino acids, drugs and flavonoids are reviewed and compared. Based on the papers reviewed, it is clear that cyclodextrins are promising molecular recognition agents in the creation of electrochemical sensors, chiral sensors, and biosensors. Moreover, they have been combined with a host of materials to enhance the detection of the target analytes. Nevertheless, challenges remain, including the development of more robust methods for the integration of cyclodextrins into the sensing unit.

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Section: Cyclodextrin-based Biosensorsmentioning

confidence: 99%

Section: Cyclodextrin-based Biosensorsmentioning

confidence: 99%

Section: Cyclodextrin-based Biosensorsmentioning

confidence: 99%

Section: Enantioselective Cyclodextrin-based Electrochemical Sensorsmentioning

confidence: 99%

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Cyclodextrins as Supramolecular Recognition Systems: Applications in the Fabrication of Electrochemical Sensors

et al. 2021

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“…A CD-modified glassy carbon electrode for trans -resveratrol detection has been engineered for single-use applications; trans -resveratrol adsorbed strongly to the surface and could not be removed by polishing or cleaning the electrode . Other CD–metal surfaces, such as CD self-assembled monolayers with thiolated CDs or CD surface free-radical polymerization, are also single-use due to strong analyte complexation, and the surface needs to be abated or polished for reuse applications. − …”

Section: Introductionmentioning

confidence: 99%

Reusable Cyclodextrin-Based Electrochemical Platform for Detection oftrans-Resveratrol

Panahi

Merrill

Halpern

2020

ACS Appl. Polym. Mater.

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A reusable sensor architecture, through the combination of self-assembled monolayers and cyclodextrin supramolecular interactions, is demonstrated for class recognition of hydrophobic analytes demonstrated with trans-resveratrol. The reloadable sensor is based on the reversible immobilization of α-cyclodextrin on the polyethylene glycol surface. α-Cyclodextrin complexes with polyethylene glycols and causes the polymer chains to change their surface configuration. The reproducibility and stability of the surface, in the detection of nanomolar concentrations of trans-resveratrol, can be demonstrated by electrochemical impedance spectroscopy, X-ray photoelectron spectroscopy, and attenuated total reflectance–Fourier transform infrared spectroscopy. We propose that during sensor operation, α-cyclodextrin decouples from the poly-ethylene glycol surface to complex with trans-resveratrol in solution, and after use, the surface regeneration is conducted with a simple α-cyclodextrin soak. To test the nonspecific response, the sensor was also tested with trans-resveratrol-spiked human urine.

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Development of paper devices with conductive inks for sulfanilamide electrochemical determination in milk, synthetic urine, and environmental and pharmaceutical samples

Lisboa

Faria

Alves

et al. 2021

J Solid State Electrochem

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Cyclodextrin subject-object recognition-based aptamer sensor for sensitive and selective detection of tetracycline

Cited by 14 publications

References 39 publications

Cyclodextrins as Supramolecular Recognition Systems: Applications in the Fabrication of Electrochemical Sensors

Cyclodextrins as Supramolecular Recognition Systems: Applications in the Fabrication of Electrochemical Sensors

Reusable Cyclodextrin-Based Electrochemical Platform for Detection oftrans-Resveratrol

Development of paper devices with conductive inks for sulfanilamide electrochemical determination in milk, synthetic urine, and environmental and pharmaceutical samples

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