2024
DOI: 10.1111/obr.13687
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Cyclodextrins as therapeutic drugs for treating lipid metabolism disorders

Jiao Wu,
Jingyi Li,
Wenxiang Shao
et al.

Abstract: SummaryObjectiveThis study sought to systematically compare the efficacy and mechanism of cyclodextrins as drug interventions in lipid metabolism diseases, potentially providing ideas for subsequent research directions and clinical applications.MethodsWe used the bibliometric method for feature mining, applied VOSviewer software for clustering analysis, and applied content analysis for objective descriptions and accurate analysis.Results(1) We collected more than 50 studies, which is the basic database of this… Show more

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Cited by 3 publications
(1 citation statement)
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“…However, the solubility of β-CD in water is constrained because of the interaction of internal hydrogen bonds, which restricts its use in parenteral products. The β-CD derivatives such as M-β-CD, HP-β-CD and SBE-β-CD have been used and developed into corresponding marketed formulations to overcome this problem [ 18 , 64 ]. Recently, β-CD derivatives have been incorporated into a range of nano-sized formulations, which have the characteristics of excellent drug loading capacity, low toxicity and long blood circulation time, and show great potential in terms of atherosclerosis treatment [ 65–67 ].…”
Section: Methodsmentioning
confidence: 99%
“…However, the solubility of β-CD in water is constrained because of the interaction of internal hydrogen bonds, which restricts its use in parenteral products. The β-CD derivatives such as M-β-CD, HP-β-CD and SBE-β-CD have been used and developed into corresponding marketed formulations to overcome this problem [ 18 , 64 ]. Recently, β-CD derivatives have been incorporated into a range of nano-sized formulations, which have the characteristics of excellent drug loading capacity, low toxicity and long blood circulation time, and show great potential in terms of atherosclerosis treatment [ 65–67 ].…”
Section: Methodsmentioning
confidence: 99%