Cyclopeptide alkaloids from Zizyphus nummularia

Pandey, Vaibhav; Singh, Jagdish P.; Seth, K. K.; Shah, Abdul Haleem; Eckhardt, G.

doi:10.1016/s0031-9422(00)85003-7

Cited by 21 publications

(21 citation statements)

References 4 publications

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“…The structure of sativanine-M was thus settled as 1 which is an isomer of rugosanine-A (2). The structure was further supported by deformylation of 1 into a known alkaloid sativanine-C (3) [7]. …”

Section: Resultsmentioning

confidence: 97%

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Cyclopeptide alkaloids fromZizyphus sativabark

Pandey

Singh

et al. 2008

Natural Product Research

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Section: Resultsmentioning

confidence: 97%

“…Dried stem bark (4 g) was extracted as described earlier [7]. The obtained alkaloid mixture (2.5 kg) was fractionated on a SiO 2 -gel (150 g) column eluting with increasing polar CHCl 3 -MeOH mixtures.…”

Section: Extraction and Isolationmentioning

confidence: 99%

Cyclopeptide alkaloids fromZizyphus sativabark

Pandey

Singh

et al. 2008

Natural Product Research

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“…For that reason, it is natural to seek effective transport pathways for S among the fluid transport pathways. To this end, it is convenient to represent (11) in coordinates that are co-moving with the fluid. Let Φ t t0 : x 0 → Φ t t0 (x 0 ) denote the (particle) flow map, which takes fluid particles from their initial location x 0 at time t 0 to their spatial location x at time t in correspondence withẋ = u(x, t).…”

Section: A Lagrangian Passive Scalar Transport Perspectivementioning

confidence: 99%

“…This particular setting contains already many of the properties which can be observed in natural flows. One is the formation of large-scale coherent patterns when RBC is investigated in horizontally extended domains [6][7][8][9][10][11]. These coherent sets, which have been detected in the Eulerian frame of reference, are termed turbulent superstructures as the characteristic horizontal scale extends the height of the convection layer.…”

Section: Introductionmentioning

confidence: 99%

Lagrangian coherent sets in turbulent Rayleigh-Bénard convection

et al. 2019

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Coherent circulation rolls and their relevance for the turbulent heat transfer in a two-dimensional Rayleigh-Bénard convection model are analyzed. The flow is in a closed cell of aspect ratio four at a Rayleigh number Ra = 10 6 and at a Prandtl number Pr = 10. Three different Lagrangian analysis techniques based on graph Laplacians -distance spectral trajectory clustering, time-averaged diffusion maps and finite-element based dynamic Laplacian discretization -are used to monitor the turbulent fields along trajectories of massless Lagrangian particles in the evolving turbulent convection flow. The three methods are compared to each other and the obtained coherent sets are related to results from an analysis in the Eulerian frame of reference. We show that the results of these methods agree with each other and that Lagrangian and Eulerian coherent sets form basically a disjoint union of the flow domain. Additionally, a windowed time-averaging of variable interval length is performed to study the degree of coherence as a function of this additional coarse graining which removes small-scale fluctuations that cause trajectories to disperse quickly. Finally, the coherent set framework is extended to study heat transport.

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“…Zizyphine E (52) [191,192] Zizyphine F [192,193] Zizyphine G [192,193] Zizyphine I (31) [194] Abyssinine A [191,192] Abyssinine B [191,192] (stem bark) Mauritine D [195] Frangufoline [195] Amphibine B [195] Zizyphus nummularia (root bark) Nummularine B [196] Nummularine D (38) [197] Nummularine E (35) [197] Nummularine F (32) [197] Nummularine M (36) [196] Nummularine N (16) [196] Jubanines A and B [198] Mauritines C and F [198] Frangufoline [198] Amphibine A [198] Integerrenine [198] N-demethyl-jubanine B = Nummularine O (18) [198,199] (stem bark) Jubanine B [200,201] Mauritine D [200,201] Nummularine P (26) [200,201] Nummularine S (10) [200] (bark) Nummularine T (19) N-formyl cyclic peptide [202] Zizyphus hysodrica (bark)…”

Section: Family (Species) Constituents Structures Bioactivity Referencesmentioning

confidence: 99%

Naturally-Occurring Cyclopeptides: Structures and Bioactivity

Pomilio¹,

Battista²,

Vitale

2006

COC

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Cyclic peptides are a special bioactive group of compounds with interesting pharmacological and biochemical properties. Different natural sources are mentioned in this paper, but interest is focused on those cyclopeptides isolated from higher plants and higher fungi. Cyclopeptides occur in higher plant species, which belong to the following families: Annonaceae, Araliaceae, Asteraceae, Caryophyllaceae, Euphorbiaceae, Fabaceae, Labiatae, Linaceae, Olacaceae, Rhamnaceae, Rubiaceae, Rutaceae, Schizandraceae, Solanaceae, and Violaceae. Basidiomycetes is the group of higher fungi, which has shown to be rich in cyclopeptides, e.g., Amanita, Conocybe, Lepiota, Galerina, and Omphalotus species. Usually these compounds are associated to a toxic response in mammals, as well as to cytotoxic, insecticidal, antimalarial, estrogenic, sedative, nematicidal, antimicrobial, immunosuppressive, and enzyme-inhibitory activities. Structures are elucidated by chemical methods and spectroscopic techniques. Configurational and conformational analyses of some bioactive cyclopeptides are discussed. Conformational studies of the natural cyclopeptides and their derivatives are related to the stereochemical requirements for these bioactive compounds.

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Cyclopeptide alkaloids from Zizyphus nummularia

Cited by 21 publications

References 4 publications

Cyclopeptide alkaloids fromZizyphus sativabark

Cyclopeptide alkaloids fromZizyphus sativabark

Lagrangian coherent sets in turbulent Rayleigh-Bénard convection

Naturally-Occurring Cyclopeptides: Structures and Bioactivity

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