Cyclosporin 2-hr post dose monitoring-a potentially valuable tool for optimising immunosuppresssion after heart transplantation

Optimizing the immunosuppressive regimen in heart transplantation

“…21 Recent studies have confirmed these findings. [22][23][24] In a further study of 314 stable heart transplant patients, C 2 monitoring has been shown to correlate more closely than C 0 with the cyclosporine microemulsion dose, renal function and acute rejection, and to be less variable than C 0 within individual patients. 25 The clinical benefits of C 2 -based monitoring already seen in renal and liver transplantation also appear to be promising in heart transplant recipients.…”