Cyclotron production of no-carrier-added 206Bi (6.24 d) and 205Bi (15.31 d) as tracers for biological studies and for the development of alpha-emitting radiotherapeutic agents

Lagunas-Solar, Manuel C.; Carvacho, Omar F.; Nagahara, Larry A.; Mishra, Aakash; Parks, Norris J.

doi:10.1016/0883-2889(87)90008-6

Cited by 26 publications

(12 citation statements)

References 9 publications

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“…Especially looking at the bismuth isotopes produced, one clearly sees the influence of the increasing number of lead isotopes contributing to the production of the lighter bismuth isotopes. Only for the nat Pb( p, xn) 205 Bi and nat Pb( p, xn) 206 Bi reactions previous measurements were performed by Lagunas-Solar et al [19] and Deptula et al [20]. In general, the agreement between [19] and our data is good, except for their reported minimum in the 205 Bi production located around 28 MeV, which is not visible either in our measurements or in the model calculations.…”

Section: Resultssupporting

confidence: 74%

“…Only for the nat Pb( p, xn) 205 Bi and nat Pb( p, xn) 206 Bi reactions previous measurements were performed by Lagunas-Solar et al [19] and Deptula et al [20]. In general, the agreement between [19] and our data is good, except for their reported minimum in the 205 Bi production located around 28 MeV, which is not visible either in our measurements or in the model calculations. The results from [20] tend to be lower than ours, which may be caused by the method of flux monitoring used by Deptula et al For clarity those values are not given in the figures, a detailed discussion can be found in [13].…”

Section: Resultssupporting

confidence: 74%

“…We performed the calculations with different parameter sets, de- [19,20] are not shown here. For a discussion see text.…”

Section: Resultsmentioning

confidence: 99%

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Thin target cross sections for proton-induced formation of radionuclides from lead for E _p≤71 MeV

Kuhnhenn¹,

Herpers²,

Glasser³

et al. 2001

Radiochimica Acta

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Proton-induced nuclide formation from lead / Integral cross section measurements / Nuclear model calculations / Nuclear reaction mechanismsSummary. Some new cross sections for proton-induced radionuclide formation from lead are presented. The results extend the previous measurements from about 70 MeV down to threshold energies. Emphasis was placed upon an improved method of γ -ray spectrum analysis which proved to be reliable and effective. The new results are compared with model calculations on the basis of an improved hybrid model of preequilibrium reactions which is able to reproduce the near target products very well. But for more than 6 emitted nucleons, experimental measurements are superior.

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Section: Resultssupporting

confidence: 74%

Section: Resultssupporting

confidence: 74%

See 1 more Smart Citation

Thin target cross sections for proton-induced formation of radionuclides from lead for E _p≤71 MeV

Kuhnhenn¹,

Herpers²,

Glasser³

et al. 2001

Radiochimica Acta

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“…[1][2][3][4]) and lead (cf . [5][6][7][8]). The data for brass were measured in our laboratory [10].…”

Section: Introductionmentioning

confidence: 97%

“…Excitation functions for the formation of activation products in high-energy protoninduced reactions have been measured for several elements (cf . [1][2][3][4][5][6][7][8][9][10]), among them titanium (cf . [1][2][3][4]) and lead (cf .…”

Section: Introductionmentioning

confidence: 99%

Excitation functions of nuclear reactions leading to the soft-radiation emitting radionuclides⁴⁵Ca,⁴⁹V and²⁰⁴Tl in beam collimator materials used in proton therapy

Qaim¹,

Kettern

Shubin

et al. 2010

Radiochimica Acta

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Proton induced reaction / Excitation function /Collimator materials Ti and Pb / Activation products 45 Ca, 49 V and 204 Tl / Radiochemical separation / Nuclear model calculation Summary. Cross sections of nuclear reactions leading to the formation of the soft-radiation emitting radionuclides 45 Ca (T 1/2 = 163 d; β − = 260 keV), 49 V (T 1/2 = 330 d; K α = 4.51 keV) and 204 Tl (T 1/2 = 3.78 a; β − = 763 keV) in proton induced reactions on titanium and lead, respectively, often used as collimators in proton therapy facilities, were measured for the first time over the energy range extending up to 200 MeV. Use was made of the stacked-foil technique. Elaborate radiochemical separations were performed and the radioactivity of the products was determined via anticoincidence beta counting, liquid scintillation counting or X-ray spectrometry. The experimental data were compared with the results of nuclear model calculations using the codes ALICE-IPPE and TALYS. In general good agreement was obtained. In the case of 204 Tl, however, the calculated values from ALICE-IPPE in the energy region above 80 MeV deviated considerably from the experimental data, possibly due to strong contributions of multiple particle emission reactions.

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Bi-labelled antibody and Bi-labelled streptavidin. Comparison of targeting efficacy of a lymphoma cell line in vitro

Henriksen

Funderud

Hoff

1997

J Label Compd Radiopharm

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Cyclotron production of no-carrier-added 206Bi (6.24 d) and 205Bi (15.31 d) as tracers for biological studies and for the development of alpha-emitting radiotherapeutic agents

Cited by 26 publications

References 9 publications

Thin target cross sections for proton-induced formation of radionuclides from lead for E _p≤71 MeV

Thin target cross sections for proton-induced formation of radionuclides from lead for E _p≤71 MeV

Excitation functions of nuclear reactions leading to the soft-radiation emitting radionuclides⁴⁵Ca,⁴⁹V and²⁰⁴Tl in beam collimator materials used in proton therapy

Bi-labelled antibody and Bi-labelled streptavidin. Comparison of targeting efficacy of a lymphoma cell line in vitro

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Cyclotron production of no-carrier-added 206Bi (6.24 d) and 205Bi (15.31 d) as tracers for biological studies and for the development of alpha-emitting radiotherapeutic agents

Cited by 26 publications

References 9 publications

Thin target cross sections for proton-induced formation of radionuclides from lead for E p≤71 MeV

Thin target cross sections for proton-induced formation of radionuclides from lead for E p≤71 MeV

Excitation functions of nuclear reactions leading to the soft-radiation emitting radionuclides45Ca,49V and204Tl in beam collimator materials used in proton therapy

Bi-labelled antibody and Bi-labelled streptavidin. Comparison of targeting efficacy of a lymphoma cell line in vitro

Contact Info

Product

Resources

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Thin target cross sections for proton-induced formation of radionuclides from lead for E _p≤71 MeV

Thin target cross sections for proton-induced formation of radionuclides from lead for E _p≤71 MeV

Excitation functions of nuclear reactions leading to the soft-radiation emitting radionuclides⁴⁵Ca,⁴⁹V and²⁰⁴Tl in beam collimator materials used in proton therapy