Cystadenofibroma of the Ovary. A Clinicopathologic Study of 34 Cases and Comparison With Serous Cystadenoma

Czernobilsky, Bernard; Borenstein, Ρ; Lancet, M

doi:10.1097/00006254-197507000-00024

Cited by 25 publications

(45 citation statements)

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“…Of our 28 patients, all but 6 were 40 years of age or over (78.6%) and all but 10 were 50 years of age or over (63.3%) similar to other reported cases [1,2,3,5]. Ovarian cystadenofibromas occurred in the older population with only 2 patients below the age of 20 years (12 and 18 years) in our patients.…”

Section: Discussionsupporting

confidence: 86%

“…In addition, the degree of epithelial proliferation and its relation to the stromal component of the tumor are used in the classification as benign, borderline, and malignant tumors [4], although most reported ovarian cystadenofibromas were usually benign [1,2,3,4,5,6]. Since Wolfe first reported two adenofibromas, solid variants of cystadenofibromas, as a distinct entity in 1927 [7], many clinicopathologic studies have described clinical and pathologic features of ovarian cystadenofibromas [5,8,9,10]; however, a small number of studies have described the imaging findings of ovarian cystadenofibromas on ultrasound or MR imaging [6,11,12].…”

Section: Introductionmentioning

confidence: 99%

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CT and MRI findings of cystadenofibromas of the ovary

et al. 2004

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The aim of this study was to assess imaging findings on CT or MR images of histologically proven ovarian cystadenofibromas. In the period 1995-2001, 32 histologically proven ovarian cystadenofibromas were identified in 28 women. Of the 32 ovarian cystadenofibromas, 16 tumors were purely cystic and the remaining 16 were complex cystic on CT or MR images. Solid components of 16 complex cystic tumors were seen as nodular ( n=8) or trabecular ( n=9) solid areas. One tumor had both nodular and trabecular solid components. Among 16 complex cystic tumors, 14 had thick or irregular septa; thus, half of ovarian cystadenofibromas had morphological imaging features of malignancy on CT or MR images. On histology, solid components in the cystic tumors were correlated with fibrous stromas that occasionally made a false-positive result for malignancy on imaging.

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Section: Discussionsupporting

confidence: 86%

Section: Introductionmentioning

confidence: 99%

CT and MRI findings of cystadenofibromas of the ovary

et al. 2004

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“…Although ovarian cysts over 10 kg are rare with the advent of modern health care imaging, the most common etiology of benign tumors -cystic and otherwise -includes mature teratomas, fibromas, serous cystadenomas, mucinous cystadenomas, and Brenner tumors [4,5]. Ovarian serous cystadenofibromas as described here are characterized by a prominent fibrous tissue component in addition to the epithelial elements [6]. Despite the tumor size, histologically these cysts are benign and account for about 1.7% of all benign ovarian tumors [7].…”

Section: Case Report Discussionmentioning

confidence: 84%

Management of a Giant Cystic Mass in a Young Otherwise Healthy Woman

Gaffey¹,

Raper²

2018

ACRI

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A 22-year-old female student presented with pain, early satiety, a dragging sensation in the abdomen, and weight gain. She had been diagnosed with irritable bowel syndrome several years prior based on the symptoms. Over the preceding 6 months, she reported increasing frequency of progressive nausea primarily with meals, emesis nearly every day, and constipation. She noted early satiety but no evidence of dysphagia or odynophagia. Overall, she had a 20-pound weight gain within 4 months prior to diagnosis. The patient had no significant past medical or surgical history. Within her family history, there was no history of ovarian disease, gastrointestinal malignancies, or cystic disease. She reported regular menstrual cycle with an age of menarche of 12. A pregnancy test at admission was negative. Prior to diagnosis she had taken to wearing exclusively yoga pants because belts were uncomfortable.Physical examination was notable for diffuse abdominal distention and a fluid wave without peritonitis or evidence of a hernia. Percussion was dull throughout. A CT scan of the abdomen and pelvis noted a large cystic mass with internal attenuation, occupying the majority of the abdomen with mass effect resulting in superior displacement of the liver, spleen, stomach, as well as the majority of the small bowel located in the left side of the abdomen (Figure 1). Tumor marker studies, including beta-HCG, CA 19-9, carcinoembryonic antigen, and CA125 were negative.After discussion of options including a laparoscopic approach, and the small but real risk of a cancer diagnosis, an open approach was judged best to avoid rupture of the cyst. The patient was taken to the operating room for an exploratory laparotomy. A 40-cm cyst arising from the right ovary was noted (Figure 2) and on full inspection of the abdomen there was a normal appearing uterus, normal left ovary and fallopian tube, normal pelvis and paraaortic lymph nodes, normal peritoneum, and normal bowel. Gynecologists, having obtained prior consent, performed a right oophorectomy and salpingectomy in continuity with the mass. She recovered rapidly with normal dietary intake. The final pathology of the 10.4 kg cyst was serous cystadenofibroma and ovary with hemorrhagic corpus luteum. AbstractWe report a new perspective on the case of a 22-year-old female with no significant medical history who posed a diagnostic and therapeutic challenge; a giant cystic mass of the abdominal cavity. Work up was notable for no significant laboratory abnormalities but a large cystic lesion noted on imaging. The patient underwent open resection. A giant cystic abdominal tumor may present with the common and protean abdominal symptoms of bloating, pain, and early satiety from either mass effect or adhesions to surrounding structures. Caution is advised in attempting the laparoscopic resection of such tumors.

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“…1,5 AF and CAF may appear as predominantly solid masses or as cystic masses with solid components. 6,7 Black sponge-like appearance is a characteristic MR manifestation of ovarian AF and CAF and consists of tiny foci of high intensity within solid components of very low intensity on T 2 -weighted images; these foci re‰ect scattered small cystic glandular structures within denseˆbrous stroma.…”

Section: Discussionmentioning

confidence: 99%

Clear Cell Adenocarcinoma Arising from Clear Cell Adenofibroma of the Ovary: Value of DWI and DCE-MRI

et al. 2013

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Clear cell adenoˆbroma (CCAF) is a rare surface epithelial-stromal tumor of the ovary and recently considered another precursor of clear cell adenocarcinoma (CCA) other than endometrioma. We report magnetic resonance (MR)ˆndings of a borderline CCAF that contained a small CCA focus. The tumor manifested a characteristic``black sponge'' appearance. The CCA focus showed high signal intensity on diŠusion-weighted imaging (DWI) and early enhancement on dynamic contrast-enhanced (DCE) MR imaging (DCE-MRI), and the CCAF components showed low signal intensity on DWI and gradually increasing contrast enhancement on DCE-MRI.

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Cystadenofibroma of the Ovary. A Clinicopathologic Study of 34 Cases and Comparison With Serous Cystadenoma

Cited by 25 publications

References 0 publications

CT and MRI findings of cystadenofibromas of the ovary

CT and MRI findings of cystadenofibromas of the ovary

Management of a Giant Cystic Mass in a Young Otherwise Healthy Woman

Clear Cell Adenocarcinoma Arising from Clear Cell Adenofibroma of the Ovary: Value of DWI and DCE-MRI

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