“…Among the previously recorded cases the most common symptoms were (a) pain, generally of a vague character, and indefinitely related to meals; (b) dyspeptic symptoms attributable to disease in the biliary tract, such as gallstones; (c) a palpable mass; (d) a diabetic si ndrome of variable severity (Carling and Hicks, 1925;Bowers et al, 1942;Benson and Gordon, 1947;Jemerin and Samuels, 1948;Herrman and Asbell, 1949;Johnson and Gibson, 1950). In all these cases one or other of the first three complaints caused the patient to come under the care of a surgeon from the outset; the diabetic state was usually associated with the main symptom, and indicated that the pancreas was involved in the pathological process.…”