BACKGROUND Mass lesions of the breast require sonological evaluation in women of any age group. It is difficult to reach a diagnosis of the cause of the mass lesion without ultrasonographic correlation. This study aims at evaluating subjects who underwent ultrasonography for evaluation of cystic mass lesion of the breast. Objective-To evaluate subjects presented with cystic lesions of the breast using ultrasonography and to understand the management of different types of cystic lesions of breast. MATERIALS AND METHODS 80 sonologically detected cystic lesions of the breast were enrolled in the study and were followed up for a minimum period of 6 months. Study was conducted after IEC approval and written informed consent was obtained from each study participant. RESULTS Majority of the study subjects (36.25%) were in the age range of 41-50 years. 53.75% of the study subjects had simple cysts. 88.3% of the study subjects with simple cysts underwent needle aspiration and 5 cysts required excision. 3 subjects with simple cysts required aspiration more than once. Two of the three subjects with galactocoele underwent aspiration and one subject developed infection which required antibiotics and excision. Intracystic papillary carcinoma were detected in 21.25% and invasive ductal carcinoma were seen in 20% of the study subjects. CONCLUSION The age group of patients presented with cystic lesions of breasts indicate probable lower awareness regarding self-examination of the breasts after 30 years of age. This is a matter of concern. Breast cysts are usually benign though some radiologically complex masses may be malignant. Another differential diagnosis could be tuberculosis which has to be kept in mind.