Cystic lesions of the parotid gland: radiologic-pathologic correlation according to the latest World Health Organization 2017 Classification of Head and Neck Tumours

Takita, Hirotaka; Takeshita, T.; Shimono, Taro; Tanaka, Hiroko; Iguchi, Hiroyoshi; Hashimoto, Shigeo; Kuwae, Yuko; Ohsawa, Masahiko; Miki, Yukio

doi:10.1007/s11604-017-0678-z

Cited by 24 publications

(23 citation statements)

References 56 publications

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“…The histological structure of WT, composed of both cystic and solid components of epithelium and lymphoid stroma forming papillary projections, has a characteristic appearance on the radiological imaging of WT . Thus, just as on US, anechoic areas of WT microcysts also have a characteristic appearance on the MRI, where these microcysts correspond to areas of T1 hyperintensity, T2 hypointensity and low apparent diffusion coefficient signal . Apparent diffusion coefficient, a parameter of DWI, has recently been proposed for WT radiological score and for differentiation between WT and pleomorphic adenoma and carcinomas .…”

Section: Wt Scintigraphy and Radiological Diagnosticsmentioning

confidence: 99%

Cytopathology and diagnostics of Warthin's tumour

Sučić

Ljubić²,

Perković³

et al. 2020

Cytopathology

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Warthin's tumour (WT) is a benign epithelial salivary tumour, one type of salivary adenoma. Histologically, WT is structured of two components, epithelial tissue that often lines cystic formations and lymphoid tissue in the tumour stroma. FNA is a reliable diagnostic approach in the diagnosis of salivary gland lesions allowing a highly accurate categorization of benign tumour‐like lesions, benign tumours and malignant tumours. In the proposed Milan reporting system of salivary gland lesions, WT is categorized in the IVA group of benign neoplasms. Accurate cytological diagnosis is straightforward when three characteristic components are present: oncocytes, either isolated or associated in clusters, lymphocytes and lymphoid cells and often an inflammatory/necrotic‐like substance. Also, specific features of scintigraphy and radiological imaging contribute to the diagnosis of WT. WT is categorized according to Seifert G. et al in 4 types, depending on the proportions of the epithelial component and lymphoid stroma. Differential cytopathological and pathohistological diagnosis include other salivary gland lesions with lymphoid, oncocytic epithelial and cystic components. In some cases, such as the metaplastic WT variant, there are additional cytopathological and histological diagnostic difficulties. Moreover, bilateral, multicentric or multiple and infrequently seen extra‐salivary localizations of WT are associated with further cytopathological diagnostic difficulties. Also, a rare possibility of malignant transformation of the epithelial or lymphoid component of WT as well as possible association with other primary tumours remains a challenge in accurate cytopathological and histological diagnosis of WT.

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Section: Wt Scintigraphy and Radiological Diagnosticsmentioning

confidence: 99%

Cytopathology and diagnostics of Warthin's tumour

Sučić

Ljubić²,

Perković³

et al. 2020

Cytopathology

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“…Pleomorphic adenoma is the most common benign neoplasm affecting the parotid gland 2,15 . It presents a predilection for the female gender in a variable proportion found in the literature, with an average of around 1,5:1, and although it can be found in all ages, it occurs more frequently from 4 th to 6 th decade of life 6,9,20 . The clinical case described in this study corroborates the epidemiological profile of the patients described in the literature.…”

Section: Discussionmentioning

confidence: 97%

“…Due to the fact that PA is a slow and asymptomatic growth lesion, it often leads to late demand for medical care and diagnosis of lesion 5,6 . The great majority (90%) of pleomorphic adenomas affect the gland superficial lobe, being 80% in its lower portion 22 .…”

Section: Discussionmentioning

confidence: 99%

“…Salivary glands tumors (SGT) play a prominent role in human neoplasms, although uncommon, comprise an important area of oral pathology and represent one of the most interesting and challenging tumor groups in the head and neck region 1,2 . SGTs have an annual incidence in the west ofrom 2.5 to 3.0 cases for every 100.000 persons [3][4][5][6][7] .…”

Section: Introductionmentioning

confidence: 99%

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Conservative Surgical Approach to Pleomorphic Adenoma in Parotid Gland: Case Report

et al. 2020

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Abstract Pleomorphic adenoma is a benign neoplasm of the salivary glands that affects most frequently females in the fourth and sixth decade of life. As it is usually an asymptomatic lesion, it is diagnosed upon routine physical examination. Treatment consists of surgical removal with partial or total involvement of the parotid gland. Conservative enucleation is the least invasive surgical option for this type of lesion. The present work aimed at reporting a case of pleomorphic adenoma of the parotid gland with eight years of evolution. The tumor was treated conservatively. Patient has been followed for sixth months, and no sensory alterations, fistulae, clinical signs of recurrence, nor any other alterations have been observed so far. Due to the lesion benign nature, an evolution with favorable prognosis is expected. Keywords: Adenoma. Neoplasms. Salivary Glands. Resumo O Adenoma pleomórfico é uma neoplasia benigna de glândulas salivares, que acomete com maior frequência pessoas do sexo feminino entre a quarta e sexta década de vida. Por se tratar de uma lesão muitas vezes assintomática, geralmente é descoberta através do exame físico de rotina. O seu tratamento consiste em remoção cirúrgica podendo envolver ou não a glândula parótida de maneira parcial ou total. A enucleação conservadora é a modalidade cirúrgica menos invasiva para este tipo de lesão. O presente trabalho tem por objetivo relatar um caso de adenoma pleomórfico em glândula parótida com oito anos de evolução. O tumor foi tratado de maneira conservadora. A paciente está sendo acompanhada há 6 meses e não foram observados até momento alterações sensoriais, fistulas, indícios clínicos de recidiva ou qualquer outra alteração. Devido ao caráter benigno da lesão, espera-se evolução com prognóstico favorável. Palavras-chave: Adenoma. Neoplasias. Glândulas Salivares.

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“…Intratumoral calcifications sometimes occur. MR imaging shows iso-to hyperintensity on T2-weighted image, and hypointensity on T1-weighted image with heterogeneous curvilinear contrast enhancement, while non-enhancing parts representing cystic areas within the tumor can also be seen (9-40%) [24][25][26].…”

Section: Imaging Findings (Fig 4)mentioning

confidence: 99%

Imaging features of benign mass lesions in the nasal cavity and paranasal sinuses according to the 2017 WHO classification

et al. 2018

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The World Health Organization (WHO) 2017 classification of head and neck tumors has been just published and has reorganized tumors of the nasal cavity and paranasal sinuses. In this classification, three new entities (seromucinous hamartoma, NUT carcinoma, and biphenotypic sinonasal sarcoma) were included, while the total number of tumors has been reduced by excluding tumors if they did not occur exclusively or predominantly in this region. Among these entities, benign tumors were classified as sinonasal papillomas, respiratory epithelial lesions, salivary gland tumors, benign soft tissue tumors, or other tumors. In contrast, inflammatory diseases often show tumor-like appearances. The imaging features of these benign tumors and tumor-like inflammatory diseases often resemble malignant tumors, and some benign lesions should be given attention in the follow-up period and before surgery to avoid recurrence, malignant transformation, or massive bleeding. Understanding the CT and MR imaging features of various benign mass lesions is clinically important for appropriate therapy. The purpose of this article is to describe the clinical characteristics and imaging features of each of clinically important nasal and paranasal benign mass lesions, as classified according to the WHO 2017 classification of head and neck tumors, along with some inflammatory diseases.

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Cystic lesions of the parotid gland: radiologic-pathologic correlation according to the latest World Health Organization 2017 Classification of Head and Neck Tumours

Cited by 24 publications

References 56 publications

Cytopathology and diagnostics of Warthin's tumour

Cytopathology and diagnostics of Warthin's tumour

Conservative Surgical Approach to Pleomorphic Adenoma in Parotid Gland: Case Report

Imaging features of benign mass lesions in the nasal cavity and paranasal sinuses according to the 2017 WHO classification

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