Cystic macular edema induced by Latanoprost

Abstract

PurposeProstaglandin analogues are powerful ocular hypotensives that can change the blood‐aqueous barrier, developing an CME in patients with some risk factor associated such as previous ocular surgery, aphakia, rupture of the posterior capsule, uveitis history, diabetic retinopathy. We present a case of CME after the administration of LatanoprostMethodsOCT‐SD were used in the diagnosis and follow‐up of the patient.ResultsA 32 years old patient, with surgery of congenital cataratas at 9 months, and treated with Latanoprost due to a open‐angle glaucoma. After one month of treatment, the patient referred decreased visual acuity on his left eye, being the exploration compatible with the development of a CME which had decreased the visual acuity to 0,4. The diagnose was confirmed by OCT. Latanoprost was suspended; It was prescribed nepafenac eyedrops each 8 hours and brimodine each 12 hours. One month later, the AV had improved to 0.7 and showed a decrease OCT macular thickness, with disappearance of cysts and recovery foveal depressionConclusionsAlthough in healthy eyes it has not been posible to establish a causal relationship between the prostaglandin analogues and the development of a CME, it looks obvious that could favor its appearance in eyes with a blood‐aqueous barrier alteration especially with previous surgery and rupture of the posterior capsule. In our case, the patient had been previously operated of congenital cataract with no IOL implantation. The OCT appears as a useful non‐invasive method for the diagnosis and follow‐up of this complication.