Cystic mediastinal tumor; a clinical study.

Hirano, Satoshi; Motohara, Toshiji; Nishibe, Toshiya; Narita, Yoshiaki; Ohkubo, T; Takahashi, Toshiyuki; Dohke, Mitsuru; Okushiba, Shunichi; Shimozawa, Eiji; Katoh, Hiroyuki

doi:10.2995/jacsurg.11.13

Cited by 4 publications

(2 citation statements)

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“…Malignancy has been reported in 2.4% of all cases with cystic findings detected by mediastinum CT [7]. Focal cystic change with thymic neoplasm, occurring in 40% of resected thymomas, is usual because thymic carcinomas and thymomas contain fluid, bleeding, and necrotic tissue with degeneration [8].…”

Section: Discussionmentioning

confidence: 99%

Middle mediastinal thymic carcinoma with cystic findings in radiologic images: a case report

et al. 2016

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BackgroundThymic carcinomas are usually detected in the anterior mediastinum. Thymic carcinoma occurring in the middle mediastinum and showing an image of a cyst is extremely rare.Case presentationA 64-year-old man with a middle mediastinal tumor detected incidentally by a CT scan was referred. Chest CT showed an entirely cystic mass in the middle mediastinum between the bilateral brachiocephalic vein and trachea. We resected the tumor completely in the right recurrent nerve because it had invaded the nerve. Immunohistochemical features showed a thymic carcinoma pattern. The final diagnosis was thymic squamous cell carcinoma occurring in the middle mediastinum.ConclusionTo our best knowledge, this is the first report of a thymic carcinoma occurring in the middle mediastinum, as demonstrated by histopathological findings with immunohistochemical features.

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Section: Discussionmentioning

confidence: 99%

Middle mediastinal thymic carcinoma with cystic findings in radiologic images: a case report

et al. 2016

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“…If degeneration is extensive, the gross appearance of the lesion is indistinguishable from that of a congenital cyst [ 8 ]. Malignancy has been reported in 2.4% of all cases, with cystic findings detected by mediastinal CT [ 26 ]. This category includes thymoma, thymic carcinoma, lymphoma, and germ cell tumors, including mature cystic teratomas.…”

Section: Pathology Of Anterior Mediastinal Cystic Lesions: Differenti...mentioning

confidence: 99%

MRI-Based Stepwise Approach to Anterior Mediastinal Cystic Lesions for Diagnosis and Further Management

et al. 2023

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As the majority of incidentally detected lesions in the anterior mediastinum is small nodules with soft tissue appearance, the differential diagnosis has typically included thymic neoplasm and prevascular lymph node, with benign cyst. Overestimation or misinterpretation of these lesions can lead to unnecessary surgery for ultimately benign conditions. nonsurgical anterior mediastinal lesions. The pitfalls of MRI evaluation for anterior mediastinal cystic lesions are as follows: first, we acknowledge the limitation of T2-weighted images for evaluating benign cystic lesions. Due to variable contents within benign cystic lesions, such as hemorrhage, T2 signal intensity may be variable. Second, owing to extensive necrosis and cystic changes, the T2 shine-through effect may be seen on diffusion-weighted images (DWI), and small solid portions might be missed on enhanced images. Therefore, both enhancement and DWI with apparent diffusion coefficient values should be considered. An algorithm will be suggested for the diagnostic evaluation of anterior mediastinal cystic lesions, and finally, a management strategy based on MRI features will be suggested.

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Apocrine adenocarcinoma arising from mature cystic teratoma in the anterior mediastinum: A case report

Ueda,

Takamochi,

Yoshimoto

et al. 2024

Pathology International

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Primary mediastinal apocrine adenocarcinoma is extremely rare, with only one case reported to date. Here, we report a surgical case of primary mediastinal apocrine adenocarcinoma. An anterior mediastinal cystic tumor with calcification was identified on chest computed tomography scan in a 51‐year‐old female patient undergoing maintenance hemodialysis. The tumor was 19 mm in size, did not invade the adjacent organs or show distant metastases, and was surgically removed. Microscopic examination revealed that the tumor cells exhibited cribriform or solid proliferation patterns with thick fibrous capsules. The tumor cells had an abundant eosinophilic cytoplasm, and decapitation secretion was noted. Immunohistochemistry revealed positivity for GCDFP‐15 and androgen receptors, with Ki‐67 positivity at 10%. The cyst wall exhibited extensive fibrosis and keratinized material, with bone and bronchial glands identified at the cyst periphery; the tumor cells were contiguous with those structures. The patient was diagnosed with apocrine adenocarcinoma arising from a mature cystic teratoma. The patient has maintained a recurrence‐free status without adjuvant therapy for 6 years after surgery. This case presents a small primary mediastinal apocrine adenocarcinoma that achieved remarkable long‐term survival.

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Cystic mediastinal tumor; a clinical study.

Cited by 4 publications

References 1 publication

Middle mediastinal thymic carcinoma with cystic findings in radiologic images: a case report

Middle mediastinal thymic carcinoma with cystic findings in radiologic images: a case report

MRI-Based Stepwise Approach to Anterior Mediastinal Cystic Lesions for Diagnosis and Further Management

Apocrine adenocarcinoma arising from mature cystic teratoma in the anterior mediastinum: A case report

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