Cystic Meningioangiomatosis

Kobayashi, Hiroyuki; Ishii, Nobuaki; Murata, Junko; Saito, Hisatoshi; Kubota, Kanako; NAGASHIMA, Kazuo; Iwasaki, Yoshinobu

doi:10.1159/000094071

Cited by 17 publications

(7 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…2,16 The pathognomonic finding of this tumor is its invasive nature, characterized pathologically by invasive meningiovascular proliferation, perivascular cuffs of spindle cell proliferation, perivascular connective tissue proliferation, and neurofibrillary tangles, often interspersed with more discrete meningiomas (3,4,9,10,12,16–21,24,26). …”

Section: Discussionmentioning

confidence: 99%

Multifocal meningioangiomatosis in a 3-year-old patient

Jamil¹,

Ramkissoon

Folkerth

et al. 2012

PED

View full text Add to dashboard Cite

Meningioangiomatosis consists of benign hamartomatous lesions of the brain and the leptomeninges, which typically present with seizure. Management is predicated on resection and control of seizures with medication. Lesions are typically solitary. Multifocal meningioangiomatosis is extremely rare, with only 2 cases reported in adults and none in children. The authors report the first case, to their knowledge, of multifocal meningioangiomatosis in a child. This unique case highlights therapeutic challenges associated with these lesions and demonstrates that multifocality is possible in the pediatric population. This finding has implications for diagnosis and follow-up for children afflicted with these tumors.

show abstract

Section: Discussionmentioning

confidence: 99%

Multifocal meningioangiomatosis in a 3-year-old patient

Jamil¹,

Ramkissoon

Folkerth

et al. 2012

PED

View full text Add to dashboard Cite

show abstract

“…Supported evidence included cysts that were eccentric to the solid mass and adjacent to sulci. However, communication between cysts and the subarachnoid space has not been confirmed in MA [ 20 ]. Another potential mechanism is enlarged perivascular spaces in which CSF gradually accumulates, eventually resulting in the formation of cysts.…”

Section: Case Presentationmentioning

confidence: 99%

Three cases of sporadic meningioangiomatosis with different imaging appearances: case report and review of the literature

et al. 2015

View full text Add to dashboard Cite

BackgroundMeningioangiomatosis (MA) is a rare meningiovascular malformation or hamartomatous lesion in the central nervous system. Radiographic findings of MA may show a variety of characteristics according to different histological components. We present three cases of sporadic MA with different imaging appearances in an attempt to identify specific imaging characteristics.Case presentationIn case 1, an irregular hyperdense solid mass was localized in the left middle cranial fossa, demonstrating low and equal signal intensity on T1-weighted imaging (T1WI; TR/TE 2,048.9 ms/26.1 ms), high signal intensity with multiple flow void effect on T2-weighted imaging (T2WI; TR/TE 4,000 ms/106.4 ms), and significant and homogeneous enhancement on post-contrast magnetic resonance imaging (MRI). In case 2, the lesion in the right insular lobe showed a cystic-mural nodule pattern. The cystic content demonstrated similar density or signal intensity as cerebrospinal fluid, while the mural nodule demonstrated equal density or signal intensity on computed tomography (CT) and MRI. On post-contrast MRI, the mural nodule showed significant enhancement, but the cystic wall and content showed no enhancement. In case 3, a remarkably enhanced solid nodule was found in the cortex of the left parietal lobe with multiple small cysts surrounding it. This nodule showed low signal intensity on T2WI and diffusion-weighted imaging (DWI; TR/TE 6,000 ms/96.8 ms, b = 1,000 s/mm2). The preoperative diagnoses of the above three cases were meningioma, hemangioblastoma, and ganglioglioma. However, all were pathologically diagnosed as MA.ConclusionThe presented cases demonstrate that MA may present with solid and cystic imaging patterns, which may include large cystic-mural nodules and small intra- and extra-cystic patterns. Although MA imaging diagnoses are difficult, several MRI signs may include specific characteristics, such as a flow void effect on T2WI and separating cysts in the cystic MA (as shown in our cases), gyriform hyperintensity on T2-fluid attenuated inversion recovery (FLAIR) sequence, and susceptibility artifacts on T2 gradient echo (GRE) sequences (as found in the literature).

show abstract

“…(Tabla 1) Los estudios neurofisiológicos realizados a pacientes con MA esporádica han demostrado que la actividad epileptogénica puede provenir de la propia lesión, de la corteza perilesional o encontrarse en un área alejada a esta. 8,15,28 Esto pudiera explicar la persistencia de las crisis epilépticas en el postoperatorio de pacientes a los que solo se les ha realizado lesionectomía. 13 En el caso que se presenta, la MA y la corteza cerebral que la rodeaba eran epileptogénicas.…”

Section: Discussionunclassified

Meningioangiomatosis y displasia cortical focal.

Estupiñán-Díaz¹,

Ríos-Castillo²,

Chacón³

et al. 2022

revecuatneurol

View full text Add to dashboard Cite

La asociación de meningioangiomatosis (MA) con displasia cortical focal (DCF) ha sido escasamente publicada. Presentamos el caso de una adolescente de 15 años con antecedentes de epilepsia farmacorresistente de 10 años de evolución, sin historia de neurofibromatosis. La imagen de resonancia magnética mostró un aumento de volumen del hipocampo y de la región parahipocampal derecha. La lesión fue interpretada como posible tumor. Se realizó en este caso una lobectomía temporal derecha guiada por electrocorticografía (ECoG) intraoperatoria. El estudio histológico evidenció una DCF tipo IIIc (MA predominantemente vascular asociada a DCF). La paciente se encuentra libre de crisis (escala de Engel IA) luego de 4 años de evolución postquirúrgica. Ante la sospecha de MA, se recomienda realizar estudios de ECoG intraoperatoria por la posible asociación con DCF en la neocorteza perilesional lo que pudiera incrementar su incidencia y el conocimiento sobre estas dos lesiones. El estudio histológico proporciona el diagnóstico definitivo.

show abstract

Cystic Meningioangiomatosis

Cited by 17 publications

References 15 publications

Multifocal meningioangiomatosis in a 3-year-old patient

Multifocal meningioangiomatosis in a 3-year-old patient

Three cases of sporadic meningioangiomatosis with different imaging appearances: case report and review of the literature

Meningioangiomatosis y displasia cortical focal.

Contact Info

Product

Resources

About