Cysticercosis of tongue: Cytohistologic approach to diagnosis

Koteeswaran, G; Goneppanavar, Mangala; Kotasthane, Dhanajay Srikant; Tirou, Aroul T

doi:10.4103/0973-029x.125231

Cited by 8 publications

(4 citation statements)

References 4 publications

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“…Diagnosis of cysticercosis is made on fine needle aspiration cytology (FNAC) only when fragments of metacestode tegument and parenchyma are identified, which were absent in the present case. Even to suspect a parasitic infection characteristic cell type host inflammatory reaction consisting of eosinophils, neutrophils, palisading histiocytes, and giant cells must be present in the aspirate from suspicious subcutaneous nodule (Koteeswaran et al 2013). Cytochemical evaluation of cerebrospinal fluid is also of great help in extra parenchymal cysts, showing various stages of inflammatory cell reaction (increase of lymphocytes, proteins, and hypoglycorrhachia) that are important to perform prognosis before antiparasitic treatment.…”

Section: Direct Detection Of Metacestodes and Tissue Lesions In Cns A...mentioning

confidence: 99%

Recent Advances in Diagnosing of Human Cysticercosis

2023

IJAB

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Cysticercosis in humans is a parasitic disease caused by Cysticercus (C.) cellulosae, the larval stage (known as metacestode) of the Cyclophyllidean tapeworm Taenia (T.) solium. It is a highly prevalent infection in India, China, the Southern part of the African continent, South America, the Central American region of North America, and a few Eastern European countries. T. solium (neuro cysticercosis, NC) causes a zoonotic disease complex. According to many authors NC is considered as one of the most important food-borne zoonotic diseases respectively, caused by helminth parasite. Accurate and prompt diagnosis is essential for early detection and effective treatment of the disease. Diagnostic approaches including: Direct Detection of metacestodes and tissue lesions in CNS and soft tissues; Various Imaging Techniques like: CT, MRI, Ultrasonography (US) and Xray; Classical and Rapid Serology tests and Molecular techniques. Neuroimaging by CT or MRI is critical in the diagnosis of neurocysticercosis. MRI is more expensive but is becoming more accessible in developing countries often provides a clearer picture of cysticerci and has greater sensitivity for multiple lesions. Serological testing provides important confirmatory data for patients with suspicious lesions on CT or MRI. Serological testing has improved, with a sensitivity of 98% and a specificity approaching 100%. The electro-immune-transfer blot (western blot) assay using lentil lectin purified glycoprotein antigens (LLGP-EITB) is preferable to the ELISA for the identification of anti-cysticercal antibodies in human serum. Low molecular weight metacestode secretion proteins, and especially glycoproteins, have shown the best performances in NC diagnosis assays. The LAMP (loop-mediated isothermal amplification technique) test would be a very useful tool to contribute to reducing the incidence of cysticercosis in developing countries, except when the cysticerci are calcified, because in that case no circulating antigens are available. Ideally both ways are used, combining the advantage of the higher sensitivity of MRI with CT detection of calcium. Identifying of human cysticercosis is possible by collecting and analyzing laboratory results and clinical/epidemiological data strictly following Del Brutto's revised diagnostic criteria.

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Section: Direct Detection Of Metacestodes and Tissue Lesions In Cns A...mentioning

confidence: 99%

Recent Advances in Diagnosing of Human Cysticercosis

2023

IJAB

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“…[1] The word "Cysticercus" is derived from two Greek words, "Kystis" meaning cyst and "Kertos" meaning tail due to its appearance. 2 These diseases are endemic in America, Asia and Africa. It is more common in northern parts of India.…”

Section: Introductionmentioning

confidence: 99%

Diagnosis of Cysticercosis in post auricular swelling on FNAC- A case report

2020

IJPO

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Introduction: Cysticercosis, a parasitic tissue infection is caused by larva of Taenia solium (Cysticercus cellulosae). Fine needle aspiration cytology (FNAC) provides direct, specific, simplest and early diagnosis of cysticercosis and remains one of the ideal diagnostic procedure wherever the lesion can be approached easily. Case Report: We present a case of 21 year old female presented with swelling on left postauricular area for one month, which was 2×1 cm, firm, tender and mobile. USG was suggestive of infective aetiology. FNAC was done using 24-gauge needle. Whitish blood mixed aspirate was seen. Smears were wet fixed with 95% ethyl alcohol and stained with Papanicolaou stain. Cytology smears showed fragments of bluish fibrillary material with interspersed small nuclei, which were seen against background of mixed inflammatory infiltrate of neutrophils, histiocytes, lymphocytes and eosinophils. Essential for diagnosis of cysticercosis are identification of parasitic fragments which may comprise bluish, fibrillary structures, sometimes with honeycombing, calcospherules, teguments, scolex with hooklets and hyaline membrane surrounding it. Conclusion: Fine needle aspiration cytology is a low cost, outpatient procedure which helps in early diagnosis of cysticercosis. A careful search for parasitic fragments is to be made in presence of polymorphous inflammatory infiltrate composed predominantly of neutrophils, histiocytes and eosinophils.

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“…[1][2][3][4][5][6][7][8] Although tongue has abundant muscular tissue, it is not a common site for cysticercus due to its high muscular activity and metabolic rate which prevent the development of larva. 6 The background usually comprises of mixed inflammatory cells infiltrate consisting of neutrophils, eosinophils, lymphocytes, and histiocytes surrounding the fibrillary material, occasionally granulomas may also be seen. 11 Parakh et al 12…”

Section: Introductionmentioning

confidence: 99%

“…Oral cysticercosis is very rare in humans. On extensive search of literature, only 64 cases of lingual cysticercosis have been reported till date . Although tongue has abundant muscular tissue, it is not a common site for cysticercus due to its high muscular activity and metabolic rate which prevent the development of larva …”

Section: Introductionmentioning

confidence: 99%

Isolated lingual cysticercosis: A rare case diagnosed on cytology

Pujani

Hassan

Khan

et al. 2017

Diagnostic Cytopathology

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Cysticercosis is caused by larval stage of Taenia solium called cysticercus cellulosae. Cysticercosis most commonly infects skeletal muscles, subcutaneous tissues, brain and ocular tissue. On extensive search of literature, only around 64 cases of lingual cysticercosis have been reported till date. We report a case of cysticercosis of tongue in a 35-year-old male who presented with a painless, slowly growing swelling over the lateral border of tongue. Fine needle aspiration cytology revealed wavy integument of cysticercus cellulosae alongwith inflammatory cells. The findings were confirmed on histopathology. No other cystic swelling was encountered in the body on retrospective examination and investigations. This case is being presented on account of its rarity as well as the utility of FNAC as a primary diagnostic technique in evaluation of parasitic lesions.

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Cysticercosis of tongue: Cytohistologic approach to diagnosis

Cited by 8 publications

References 4 publications

Recent Advances in Diagnosing of Human Cysticercosis

Recent Advances in Diagnosing of Human Cysticercosis

Diagnosis of Cysticercosis in post auricular swelling on FNAC- A case report

Isolated lingual cysticercosis: A rare case diagnosed on cytology

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