Cystocele Repair with Platelet-Rich Plasma

Atılgan, Adeviye Elçi; Aydın, Arif

doi:10.1007/s12262-020-02459-6

Cited by 7 publications

(6 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The PRP group presented significantly lower rates of symptomatic recurrence and reoperations at 48 months’ follow-up compared to control (7.1% vs. 21.4% and 3.5% vs. 17.8%, respectively, P = 0.001 )[21 ▪ ]. Patient satisfaction according to Patient Impression of Improvement was also shown to be significantly improved in PRP group ( P = 0.012 )[21 ▪ ]. This indicated that the addition of PRP in POP prolapse repair could potentially enhance the therapeutic effect of native tissue surgery avoiding thus the adverse events of implanted synthetic materials.…”

Section: Historical Data and Current Landscapementioning

confidence: 87%

“…A recent study by Atilgan et al compared the recurrence rates among 56 patients with cystocele that were randomized to receive either anterior colporrhaphy alone or combination of repair and PRP injection into the pubovesical fascia [21 ▪ ]. The PRP group presented significantly lower rates of symptomatic recurrence and reoperations at 48 months’ follow-up compared to control (7.1% vs. 21.4% and 3.5% vs. 17.8%, respectively, P = 0.001 )[21 ▪ ]. Patient satisfaction according to Patient Impression of Improvement was also shown to be significantly improved in PRP group ( P = 0.012 )[21 ▪ ].…”

Section: Historical Data and Current Landscapementioning

confidence: 99%

See 1 more Smart Citation

Platelet rich plasma for the management of urogynecological disorders: the current evidence

Prodromidou

Grigoriadis

Athanasiou

2022

Current Opinion in Obstetrics &Amp; Gynecology

View full text Add to dashboard Cite

Purpose of reviewOur objective is to review the currently available literature on the use of platelet-rich plasma (PRP) in patients with pelvic floor disorders and to critically appraise the latest evidence on the safety and efficacy of the PRP application.Recent findingsThe evidence on the use of PRP for the treatment of stress urinary incontinence (SUI) appears promising, although limited to case series, case reports and animal studies. PRP has also been proposed to enhance the surgical outcomes of pelvic organ prolapse (POP) by native tissue repair with promising success rates. The application of PRP in other PFDs including vaginal fistulas, genitourinary syndrome of menopause (GSM), mesh exposure and lichen sclerosus has been also associated with beneficial outcomes and a favorable safety profile.SummaryThe currently available literature indicates that PRP could have a beneficial effect as a single or adjuvant treatment in patients with SUI, POP, GSM, vaginal fistula and genital lichen sclerosus with minimal adverse events. However, valid evidence is still lacking and further well-designed studies are warranted in the field to confirm the validity of the so far reported outcomes.

show abstract

Section: Historical Data and Current Landscapementioning

confidence: 87%

Section: Historical Data and Current Landscapementioning

confidence: 99%

Platelet rich plasma for the management of urogynecological disorders: the current evidence

Prodromidou

Grigoriadis

Athanasiou

2022

Current Opinion in Obstetrics &Amp; Gynecology

View full text Add to dashboard Cite

show abstract

“…For a variety of urogynecological treatments, larger randomized controlled trials are required to prove their effectiveness and safety. 9,24 In any of the investigations, there were no grave side effects discovered. Minimal adverse effects, including short and bearable discomfort during treatment, a moderate headache, little itching, and transient erythema and edema of the treated region, were seen in trials employing PRP for hair growth.…”

Section: Safety and Adverse Effectmentioning

confidence: 91%

“…In the 48-month follow-up period of Atilgan and Aydin's investigation on the effects of PRP on the treatment of cystocele, no adverse effects were seen after PRP injection. 9 Uncertainty persists over the advised number of PRP administration repetition sessions. 23 From one study to the next, the quantity and Figure 1 Action Mechanism of Platelet-Rich Blood Plasma.…”

Section: Safety and Adverse Effectmentioning

confidence: 99%

Current Evidence of Platelet-Rich Blood Plasma for Pelvic Organ Prolapse: A Review

Fakhrizal,

Simanjuntak,

Hutapea

2023

Obgynia

View full text Add to dashboard Cite

Objective: To review the current evidence of the potential use of Platelet-Rich Plasma (PRP) in the field of urogynecology, especially in POP cases.Method: This review used several databases (Google Scholar, Pubmed, and Science Direct) and searched for English and Indonesian articles in the last ten years. Articles were received in the form of case reports, observational studies and clinical trials that discussed the use of Platelet-Rich Plasma in cases of Pelvic Organ Prolapse (POP).Results: A total of three articles were included in this review.Discussion: There were two patient studies and one in vitro study. The POP patient study showed favorable results with low recurrence rates in patients who received Platelet Rich-Plasma compared to those who did not and another study that conducted a one-year evaluation found no recurrences after the patients received Platelet Rich Plasma at the surgical site. The in vitro study showed good cell attachment and proliferation in vaginal tissue biopsies with Platelet-Rich Plasma applied to the tissue.Conclusion: Platelet-Rich Plasma may promote tissue regeneration, hence potentially reduce recurrency after reconstruction.Bukti Terkini Plasma Darah Kaya Trombosit untuk Prolaps Organ Panggul: Sebuah KajianTujuan: Untuk meninjau bukti terkini mengenai potensi penggunaan Platelet-Rich Plasma di bidang uroginekologi, khususnya pada kasus POP.Metode:Tinjauan ini menggunakan beberapa database Google Scholar, Pubmed, dan Science Direct) dan mencari artikel berbahasa Inggris dan Indonesia dalam sepuluh tahun terakhir. Artikel yang diterima berupa laporan kasus, studi observasional, dan uji klinis yang membahas penggunaan Platelet-Rich Plasma pada kasus Prolaps Organ Panggul (POP).Hasil: Sebanyak tiga artikel termasuk dalam tinjauan ini.Diskusi: Terdapat dua studi pasien dan satu studi in vitro. Studi pasien POP menunjukkan hasil yang baik dengan tingkat kekambuhan yang rendah pada pasien yang menerima PRP dibandingkan dengan mereka yang tidak menerima Platelet-Rich Plasma dan studi lain yang melakukan evaluasi satu tahun tidak menemukan adanya kekambuhan setelah pasien menerima Platelet-Rich Plasma di tempat pembedahan. Studi in vitro menunjukkan perlekatan dan proliferasi sel yang baik pada biopsi jaringan vagina dengan Platelet-Rich Plasma yang diaplikasikan pada jaringan tersebut.Kesimpulan: Platelet-Rich Plasma dapat meningkatkan regenerasi jaringan, sehingga berpotensi mengurangi kekambuhan setelah rekonstruksi.Kata kunci: Platelet-Rich Blood Plasma, Prolaps Organ Panggul, Uroginekologi

show abstract

“…PRP is also found to be of use in the management of cystoceles. Considering the complications of cystoceles like mesh complications, platelet-rich plasma may serve as a good option to prevent the recurrence of cystoceles [29].…”

Section: Plateletmentioning

confidence: 99%

Platelet-Rich Plasma: A Promising Regenerative Therapy in Gynecological Disorders

Varghese¹,

Acharya²

2022

Cureus

View full text Add to dashboard Cite

Platelet-rich plasma (PRP) could be understood as a special preparation of plasma in which the concentration of platelet is immensely high. This rationale for plasma use has been in the medical science for many years with plenty of success in various fields where it was inculcated, bringing dramatically favorable and better outcomes in terms of disease management and prognosis. PRP has been widely used in orthopedics from the very beginning, but in the past few years its use has been extended to other fields too, such as obstetrics and gynecology. From the very onset of the introduction of platelet-rich plasma in gynecology, there had been constant research being carried out all around the globe in order to scientifically prove and confirm its exact role in the management of gynecological problems. Regenerative medicine in gynecology was among the first areas where the platelet-rich plasma was implemented and has substantially given great results, which encouraged further extensive research to be carried out in other spectrums of gynecology. The implications of such great struggles ultimately gave way to evidence suggesting the importance of platelet-rich plasma in managing gynecological disorders like Asherman's syndrome, urinary incontinence, genital fistulas, thin endometrium, etc. This review article collectively summarizes the various use of platelet-rich plasma in gynecology.

show abstract

Cystocele Repair with Platelet-Rich Plasma

Cited by 7 publications

References 20 publications

Platelet rich plasma for the management of urogynecological disorders: the current evidence

Platelet rich plasma for the management of urogynecological disorders: the current evidence

Current Evidence of Platelet-Rich Blood Plasma for Pelvic Organ Prolapse: A Review

Platelet-Rich Plasma: A Promising Regenerative Therapy in Gynecological Disorders

Contact Info

Product

Resources

About