Cystosarcoma Phyllodes of the Breast a Review of the Literature With the Addition of 15 New Cases

Stephenson, Hugh E.; Gross, Stanley; Gumport, Stephen L.; Meyer, Herbert W.

doi:10.1097/00000658-195211000-00009

Cited by 12 publications

(7 citation statements)

References 4 publications

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“…On the other hand, West et a1 [21] obtained excellent control with just simple mastectomy, with or without axillary dissection, in patients with malignant lesions especially those with tumors measuring 5 cm or less. This procedure is also favored by several other authors [ 1,6,17,18,22,23]. Understandably, removal of the pectoral muscles would be justified if the tumor is very close to or actually invading these muscles [ 13,171.…”

Section: Discussionmentioning

confidence: 99%

“…Statements alluding to the ineffectiveness of this modality for this particular disease have been based on sporadic reports with one or two cases in their series receiving radiotherapy [ 1, 25,26,27] or were just unfounded opinions of the authors [3,5,23,28]. Stephenson et a1 [23] stated that radiotherapy is of no value in cystosarcoma phyllodes, although the one patient in their own series who received this treatment showed no recurrence after preoperative irradiation and segmental resection. Fox [26] also stated that radiotherapy offered little help for breast sarcoma even though the use of this modality was mentioned in only one of the 60 patients in his series.…”

Section: Discussionmentioning

confidence: 99%

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Fatal metastatic cystosarcoma phyllodes in an adolescent female: Case report and review of treatment approaches

Turalba

El‐Mahdi

Ladaga

1986

Journal of Surgical Oncology

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The third reported case of fatal malignant cystosarcoma phyllodes in an adolescent female is described. The patterns of local recurrence and distant spread in this case, including the response to treatment, were similar to those reported in the first reported case in this age group. A review of the treatment recommendations for cystosarcoma phyllodes revealed that the surgical procedure of choice for the malignant variant has remained controversial, and the conclusions regarding the ineffectiveness of radiation and chemotherapy have been based on insufficient data handed down through the years. Our observations in this case and the information we have obtained from the literature have prompted us to recommend a multidisciplinary approach for malignant cystosarcoma phyllodes, particularly in young women, and we are calling for a multi-institutional study group to further investigate this disease.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Fatal metastatic cystosarcoma phyllodes in an adolescent female: Case report and review of treatment approaches

Turalba

El‐Mahdi

Ladaga

1986

Journal of Surgical Oncology

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“…Lee and Pack summarized the literature up to 1931 and found only 105 cases with an average age incidence of 44.6 years. In the Mayo clinic between 1904 and 1943 there were 13 reported cases (Stephenson et al, 1952), and the Columbia University Medical Center recorded I5 cases between 1911and 1940(Hill and Stout, 1942. These tumours have their highest incidence in the third and fourth decades (Stephenson et al, 1952).…”

Section: Incidencementioning

confidence: 99%

Giant fibro-adenoma (cystosarcoma phyllodes) in adolescent females-a clinicopathological study

Nambiar

Kutty

1974

Journal of British Surgery

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I. A n anaiysis of the findings in a series of 25 cases of giant fibro-adenoma of the breast in adolescent females is presented together with a review of the relevant literature. The clinical features, histology, prognosis and treatment of these tumours are discussed.2. Follow-up ofjrom 2 to 8 years after total excision of the tumours has shown that normal breast development occurred in all the cases. There was no recurrence or distant metastasis.3. Despite clinicaljeatures and histological characteristics suggestive of malignancy the tumour has been found in our experience to be strictly benign inpatients under the age of 20 years.

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“…Most acknowledge that "cystosarcoma' ' is an unfortunate name for this lesion because of the malignant connotation of the term. Consequently, more than 40 different names have been proposed for the disease (Adkins, 1966;Carpathios and Raftery, 1960;Stephenson et al;1952), many no doubt more suitable to the lesion. Yet, this has added confusion to the literature and makes complete reviews of the subject difficult, if not impossible.…”

Section: Introductionmentioning

confidence: 99%

Metastatic cystosarcoma phyllodes: A case report and review of the literature

Kessinger¹,

Foley²,

Lemon³

et al. 1972

Journal of Surgical Oncology

149

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The breast tumor cystosarcoma phyllodes probably does not Rpresent an entity, but rather a spectrum of disease including a benign form, a histologically malignant form, and a metastatic form. In an attempt to better understand the metastatic variant, all 66 cases which could be found in the english literature and an additional case from this institution were reviewed.The tumor often arises from a fibroadenoma, but its etiology is uncertain. Factors that determine the benignity or malignancy of the tumor are unknown, but a lower fertility rate in patients with metastases warrants interest.Incidence is low; cystosarcoma makes up about 0.5% of alI breast tumors and only 3-12% of these are metastatic.The tumor presents as a breast mass, often of large size, but there is no clinical feature peculiar to the metastatic variant.Gross and microscopic pathologic findings cannot accurately forecast the metastatic potential of the tumor, but are of more predictive value than the clinical presentation. The clinical course is the only sure means of determining metastatic potential at present.

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Cystosarcoma Phyllodes of the Breast a Review of the Literature With the Addition of 15 New Cases

Cited by 12 publications

References 4 publications

Fatal metastatic cystosarcoma phyllodes in an adolescent female: Case report and review of treatment approaches

Fatal metastatic cystosarcoma phyllodes in an adolescent female: Case report and review of treatment approaches

Giant fibro-adenoma (cystosarcoma phyllodes) in adolescent females-a clinicopathological study

Metastatic cystosarcoma phyllodes: A case report and review of the literature

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