Cytochrome P450-soluble epoxide hydrolase derived linoleic acid oxylipins and cognitive performance in type 2 diabetes

Anita, Natasha Z.; Kwan, Felicia; Ryoo, Si Won; Major-Orfao, Chelsi; Lin, William Z.; Noor, Shiropa; Lanctôt, Krista L.; Herrmann, Nathan; Oh, Paul I.; Shah, Baiju R.; Gilbert, Jeremy; Assal, Angela; Halperin, Ilana J.; Taha, Ameer Y.; Swardfager, Walter

doi:10.1016/j.jlr.2023.100395

Journal of Lipid Research

2023

DOI: 10.1016/j.jlr.2023.100395

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Cytochrome P450-soluble epoxide hydrolase derived linoleic acid oxylipins and cognitive performance in type 2 diabetes

Natasha Z. Anita,

Felicia Kwan,

Si Won Ryoo

et al.

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2024

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Cited by 5 publications

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The role of soluble epoxide hydrolase in the intestine

Ren,

Wang,

Yin

2024

Cell Biology International

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The soluble epoxide hydrolase (sEH; encoded by the EPHX2 gene) is an α/β hydrolase fold protein that is, widely distributed throughout the body. Recent studies have highlighted that sEH, in the metabolism of polyunsaturated fatty acids, plays a part in the pathogenesis of various diseases, including cardiovascular disease, Alzheimer's disease and intestine‐associated disease. This review discusses the current findings on the role of sEH in the development of intestine‐ and intestine‐associated diseases, including colitis, colorectal cancer, and other intestinal diseases, as well as the potential underlying mechanisms involved.

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The role of soluble epoxide hydrolase in the intestine

Ren,

Wang,

Yin

2024

Cell Biology International

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Cytochrome P450-soluble epoxide hydrolase oxylipins, depression and cognition in type 2 diabetes

Anita,

Herrmann,

Ryoo

et al. 2024

Journal of Diabetes and its Complications

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The Octadecanoids: Synthesis and Bioactivity of 18-Carbon Oxygenated Fatty Acids in Mammals, Bacteria, and Fungi

Revol-Cavalier,

Quaranta,

Newman

et al. 2024

Chem. Rev.

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Cytochrome P450-soluble epoxide hydrolase derived linoleic acid oxylipins and cognitive performance in type 2 diabetes

Cited by 5 publications

References 43 publications

The role of soluble epoxide hydrolase in the intestine

The role of soluble epoxide hydrolase in the intestine

Cytochrome P450-soluble epoxide hydrolase oxylipins, depression and cognition in type 2 diabetes

The Octadecanoids: Synthesis and Bioactivity of 18-Carbon Oxygenated Fatty Acids in Mammals, Bacteria, and Fungi

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