Cytodiagnosis of Gouty Tophi With Review of Literature

Singh, Meghna

doi:10.15520/ijcrr/2017/8/1/75

Cited by 1 publication

(1 citation statement)

References 7 publications

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“…Aspirate in most of the cases was chalky white, particulate, which on microscopy showed amorphous or granular myxoid material composed of MSU crystals with foamy histiocytes, multinucleated giant cells, and chronic inflammatory infiltrate . Our study demonstrated chalky white aspirate, which on microscopy of H&E stained smears revealed amorphous and myxoid material with MSU crystals, present in long needles and flower‐like clusters but we did not find associated chronic inflammatory infiltrate.…”

Section: Discussionmentioning

confidence: 43%

Gouty tophi presenting as multinodular lateral inguinal swelling: A case report

Goel

Khanna

Jain

et al. 2018

Diagnostic Cytopathology

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Fine-needle aspiration cytology (FNAC) is an important diagnostic tool which is replacing biopsy for the diagnosis of subcutaneous nodules. We present a case of 75 years old female with right sided multinodular lateral inguinal swelling since 2 years, without any clinical features of arthritis. FNAC of the lesion revealed negatively birefringent, long needle shaped monosodium urate crystals in the background of amorphous granular debris. Further investigations revealed high serum uric acid levels (9.36 mg/dL) and a confirmed diagnosis of gouty tophus was made. It is important that pathologist should be aware of the cytological features of gouty tophus, particularly in the case with unusual presentation. Gouty nodulosis has never been reported in literature at this site and we are first to report gouty tophus at this unique site.

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Section: Discussionmentioning

confidence: 43%